MARSH FAMILIES DNA PROJECT
John Marsh, Project Administrator,
ajmarsh@arrrg.org
1) Information about the DNA Project
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CONTENTS:
1) THE MARSH FAMILIES DNA STUDY: 2) PROJECT GROUP ADMINISTRATOR: 3) GOALS OF THE MARSH DNA PROJECT: 4) HOW DNA IS USED IN GENEALOGY:
5) FREQUENTLY ASKED QUESTIONS: 6) REFERENCE INFORMATION ON DNA:
7) MUTATION RATES FOR INDIVIDUAL Y-DNA MARKERS:
1) THE MARSH FAMILIES DNA STUDY:
All males pass on their Y-Chromosome DNA (Y-DNA) to their sons, mostly
unchanged. This means that all males descended on the direct male line
from the same ancestor, have identical, or nearly identical Y-DNA. By
testing the Y-DNA of Marsh males from around the World, we can find which
are related. Sometimes we can also learn about the deep ancestry of
the family, perhaps where the family may have originated, hundreds, or even
thousands of years ago, and sometimes we get indications of possible early
ancestors living hundreds of years ago.
A
MARSH FAMILES DNA PROJECT was started on 23 Sept 2003.
Males with related surnames of MASH/ MARCH/
MARIS/ MARRIS/ MARESH/ MARSCH, and variant spellings,
are also invited to participate in this project, as these surnames in some
cases have common roots to persons using the surname Marsh.
Following is a detailed description of the project, it's goals, how DNA is used for
genealogical purposes, and reference information on DNA. If you are a Marsh
interested in participating in the study, or have any questions, please contact the
Project Group Administrator, John Marsh, at
ajmarsh@arrrg.org
. We would welcome participation of any male Marshes.
.
2) PROJECT GROUP
ADMINISTRATOR:
The Project Group Administrator: John Marsh
E-mail address:
ajmarsh@arrrg.org (NOTE:
at times e-mail is not always delivered, for a variety of reasons. I normally reply
to email within 24 hours, so if you don't get a prompt reply, it is almost certain I never
received your email. If that happens, try writing to me, or try e-mailing me
again.) Postal Address: AJ Marsh, 26 Highcrest Heights, Christchurch 8025, NEW ZEALAND. Marsh Families DNA Web Site:
http://marshdna.arrrg.org
The Marsh Families DNA Project is being run on a voluntary, non profit basis, by
enthusiastic amateur genealogists, with an interest in contributing something of benefit
to the wider community of Marsh genealogists around the World. Apart from John
Marsh, there is a group of Marsh genealogist around the World, from different Marsh
families, who lend moral support, and help out in various ways. Bill Marsh in Canada,
well known for his research on Kent Marshes,
was a motivating force behind the formation of this project, and is an active supporter.
We would welcome involvement from any other Marsh genealogists, so if you feel you
have something to offer the project, in any way, we would be pleased to hear from you.
3) GOALS OF
THE MARSH DNA PROJECT, AND GENERAL INFORMATION ABOUT THE PROJECT:
-
Project for all male Marshes:
The Marsh Families DNA Project is intended for any
male with the surname of Marsh, or variant
spellings. There is evidence that Maris,
Marris,
Maresh, Marsch,
Mash, and
March
families in some cases have common roots with persons using the surname Marsh, so persons of these surnames
are also invited to participate in the project. There are 260 variant spellings
recorded for Marsh. (see
http://www.imagepartners.co.uk/Thesaurus/Search.aspx
) Sometimes the surnames of variant spelling only relate to Marsh families if they
arise in particular contexts. If anybody interested in the project has a surname
which they believe is a related variant of Marsh, please contact the Project
Administrator. Males "of surname Marsh" who may have obtained the name from adoption,
or from a maternal line, are also welcome to participate in the project. Their male
line descendants in the future will carry the name of Marsh, and may be interested to use
the results of this study to help them trace their roots.
Marsh Y-DNA Database:
The goal is to build up a database of Marsh family Y-DNA
profiles to assist Marshes world wide to trace their ancestral roots, and also locate
possible long lost branches of their families. See
http://marshdna.arrrg.org/DNAresults.htm .
Only direct male line
male Marshes can be tested- but females can help!:
The Y-DNA (Y-Chromosome DNA) tests being done through this
project only test a part of DNA which is passed on from fathers to
their sons. Females dont have Y-DNA, so are unable to be tested themselves. However,
many females of Marsh descent are interested to learn about their ancestral Marsh Y-DNA. It may be possible for them to find a known
direct male line Marsh relative (father, brother, uncle, grandfather, cousin etc) who would agree to be
tested on their behalf. We now have quite a number of females of
Marsh descend who have managed to drag a male relative into the project,
(kicking and screaming ... or even willingly). Many
thanks to these wonderful "Lady Marshes" for their support, and
contributing such a lot to the success of the project.
DNA Test Companies- Prices for the Marsh Families DNA Project Group:
The DNA testing market is becoming more competitive. Several
companies are currently being used for Y-DNA tests for this project. Each company
offers a different range of test options, testing different numbers of markers. Generally, the
more markers tested, the more useful the results, and 25 would be a desirable minimum.
However, if cost is an issue, the testing of a smaller number of markers is a good
starting point. It is recommended that interested persons contact John Marsh to
discuss which options might be appropriate, and which test company might better suit a
specific case. (Some families have distinctive family
markers tested by one test company, but not another.) Prices from the test companies below may change from time to
time. Also, periodically there are discounts or special prices offered by various
companies. Most companies have at least a small postage and
handling charge to add to costs. 1) Family tree DNA:
(NOTE: contact John Marsh at
ajmarsh@arrrg.org
to obtain access codes to obtain the following discounted prices for the Marsh Families
DNA Project if testing with FTDNA. FTDNA offer free DNA storage
for 20 years.) This test company has the most extensive range
of markers tested, and is the most frequently used test company for
surname projects. Option 1: Y-DNA12
male 12 marker paternal test $99 USA (Group price) -
STARTER
Option 2: Y-DNA25
male 25 marker paternal test $124 USA (Group price) -
GOOD Option 3: Y-DNA37
male 37 marker paternal test $149 USA (Group price) -
BETTER
(Note: Y-DNA37 promotional price $119 on offer
to 30 July 2009) Option 4: Y-DNA67
male 67 marker paternal test $248 USA (Group price) -
BEST
(Note: Y-DNA67 promotional price $199 on offer
to 30 July 2009)
2) DNA Ancestry: Information see
http://dna.ancestry.com/buykitGoals.aspx
Option 5: Y-DNA 33
marker test $79 USA-
GOOD
Option 6: Y-DNA 43
marker test $149 USA-
BETTER
3) Genebase:
Information see
http://www.genebase.com/in/dnaAncestryProjectIndex.php . Place
order at
http://www.genebase.com/order.php?is_special=c3ViLWFuY2VzdHJ5
Option 7:
Y-DNA20
male 20 marker test
$119 USA (plus postage & handling $12 min)-
GOOD
Option 8:
Y-DNA44
male 44 marker
test $199 USA (plus postage & handling $12 min)-
BETTER
4) FamilyBuilder:
Information see
http://www.familybuilder.com/ .
Prices below are for
introductory price offers from this new company as offered early in
2009, prices may change at some stage.
Option 9:
Y-DNA17
male 17 marker
paternal test $59.97 USA (plus postage etc $14.16)-
STARTER
5) DNA Heritage: (NOTE: contact John Marsh at
http://marshdna.arrrg.org
to obtain access codes to use DNA Heritage for tests, and to discuss which specific
markers should be selected. The markers set as the default setting are not the
markers preferred for the Marsh DNA Project, and these need to be adjusted.
DNA Heritage now propose to store DNA for 3 years.)
Option
10: 25 markers $149.75 USA
- GOOD Option
11:
43 markers $199 USA -
BETTER
6) EthnoAncestry:
Information see
http://www.ethnoancestry.com/
Option
12: 27 markers $248 USA
- GOOD Option
13:
45 markers $348 USA
-
BETTER
7) Genetree:
(A company affiliated with the Sorenson Molecular
Genealogy Foundation.)
https://www.genetree.com/purchase_dna_kit/product_selection
Option 14:
43 markers $149 USA
-
BETTER
8) OTHER TEST COMPANIES:
(NOTE: If someone is thinking of testing
with another test company, feel free to contact John Marsh at
ajmarsh@arrrg.org
to discuss how services compare. If you are new to DNA testing, it
might be helpful to discuss the significance of various differences in
services offered by different test companies.)
Testing is easy: Different test companies
have slightly different test kits, but most involve just rubbing a plastic scraper/ swab
on the inside of the mouth. One surname project has a photographic "how
to" guide, see... http://davedorsey.com/dna.html .
Test can be ordered on the internet, test kits are posted to the
customer, and they simply follow the instructions on how to take the
test, and post the DNA sample back to the test company.
Sponsorship:
Some interested male line Marshes have indicated that the cost prevents
them from participating, and other Marsh descendants who are not on the direct male line,
have indicated they would contribute something towards the cost of tests if a male line
Marsh relative was prepared to supply a DNA sample. If you are a Marsh male who
would participate if assistance was given with test costs, or if you are a Marsh
descendant who is prepared to contribute a donation large or small towards testing your
Marsh relatives, please contact the Project Administrator. If anybody is prepared to
make a donation towards test costs, this may have any conditions placed on it, eg that it
apply to only a specific line of a specific family. The test company Family
tree DNA has set up "general funds" for all the surname
projects who use their
company. They have set up a "Marsh General Fund" to handle donations for
DNA testing. Only the Marsh Project Administrator can authorize allocation of the
use of the money, and it can only be used for DNA testing. This system works well,
and ensures that donations are only used for their intended purpose, DNA testing. To
contribute, see www.familytreedna.com/contribution.html, but be
sure to record on the form, that the donation is to the "Marsh" fund, as there
are separate funds for about 1200 different surnames. I suggest any donors
contact me, and advise if the donation is to be restricted for use to descendants of a
particular family.
Option for
FREE DNA TESTS:
The Sorenson Molecular
Genealogy Foundation (SMGF) are conducting a DNA genealogical research project,
see
http://www.smgf.org/get_involved.jspx . They were offering
free DNA test, but they have now reached their goal of 100,000 free
tests, and are now only offering free tests in very specific
situations. They now propose focusing their resources on
analysis of samples previously obtained by them. Those
previously tested by SMGF should eventually get free access to their
results as they are processed. For those previously tested by
SMGF, and still awaiting results, there is a way to accessing their
results by paying a fee which is considerably below the normal cost
of commercial testing, see
http://www.genetree.com/dna/unlock_smgf
.
Results posted on Marsh Families DNA Web Site:
When Y-DNA test results are
available, each participant will (unless they request not to) have their results included on the Marsh Families DNA
Project web site. Participants will not be identified by name (unless they request to
be identified). The results will be identified by an anonymous number selected by the
Project Administrator. The results are shown at
http://marshdna.arrrg.org/DNAresults.htm .
Earliest known Marsh ancestor of participants:
It is expected that participants will
provide the Group Administrator with the name of the earliest known Marsh ancestor, and
the location which that ancestor was from. This information will be given on the web site
unless the participant requests that it is not shown, in conjunction with the participants
anonymous ID number, and the
results. This is an important aspect of the project, as it is through the linking of Y-DNA
to specific ancestors, and ancestral territories, that enables us to help each other to
further our knowledge of our families.
Privacy:
Privacy of participants is a very important consideration. No participant
will be named on the Web Site without authority from the participant. The group
administrator gives an undertaking to remove from the Marsh Families Web Site any
information previously supplied by an individual participant, or test results relating to
that participant, if requested to do so by the participant. If any participant has
any particular concerns about privacy, these should be able to be accommodated.
Project Administrator to have discretionary authority: The purpose of this project
is to enable kinsmen to make contact with each other, and help each other further their
knowledge of their families. It is expected that unless directed otherwise by individual
participants, the Project Administrator will have authority to discreetly arrange contact
between participants whose test results, or other circumstances, indicate possible family
connections.
Additional family history and contact information:
Participants may offer contact
information, and information on their family history or family tree, for inclusion on this
web site. The Project Administrator will attempt to incorporate this information in a
suitable way. As time allows, separate web pages will be added
where links and some family tree information can be added for specific
Marsh families. On the page at
http://marshdna.arrrg.org/DNAprojects.htm are links to some of these
specific Marsh family pages.
An evolving project:
The Marsh Families DNA Project is an evolving entity. The
Project Administrator is open to any suggestions from participants or others about how the
project might be improved.
4) HOW DNA
IS USED IN GENEALOGY:
The availability of DNA tests in recent times has offered genealogists some
exciting possibilities. In males, part of the DNA, the Y chromosome (Y-DNA), is passed on
from fathers to sons (but not to daughters) normally completely unchanged for many
generations. This means when a father passes on his surname to his son, he also passes on
his Y-DNA, which is like an invisible bar code version of the surname. If a Marsh in USA,
and a Marsh in Australia, Canada, New Zealand, England or elsewhere, had a common direct
male line ancestor 10 or 20 generations in the past, a DNA test would show that they have
identical or very similar Y-DNA.
In genealogical Y-DNA testing, typically 12, 25, 37, 43, 67 or more "markers" are tested on
the Y chromosome. However, research is rapidly advancing, and more
than 100 markers are now currently commercially available, and before long
there will be many more. There are different sorts of markers, eg STR
markers, and SNP markers. We test STR markers in the Marsh DNA
project, and some interested in their deeper ancestry have also tested SNP
markers. It is not necessary to understand how DNA works to use it for
genealogy. All you basically need to do, is see if the "marker scores"
of one person "match" another person. A close match basically means a
closer relationship. But what we are measuring in Y-DNA tests is
interesting.
In the DNA molecule, there are component molecules, each known by
different letters C, G, T, and A which are jointed together in spiral strings.
There are around 60,000,000 letters making up the Y-DNA alone, which is only
a small part of each DNA molecule. Mostly,
the strings are seemly random collections of letters. However,
sometimes parts of these strings are made up of a few letters which are
repeated. For example, one of the markers which we test is a STR
marker called DYS391. A small part of the DNA around this marker is
shown below. The part shown in blue, is STR marker DYS391. Note that
this is made up of 11 "repeats" of the 4 letters
TCTA.
When a father passes his Y-DNA on to his son, the whole 60,000,000 letters
of the Y-DNA are copied. However, sometimes when the Y-DNA is copied,
a "mutation" occurs, and one part is not copied exactly. Sometimes, in
the copying process, when half of the TCTA repeats have been copied, the
original DNA strand being copied accidentally gets slid along the copy it is
making, and gets out of line by exactly one TCTA repeat segment, and it
accidentally copies the TCTA repeats one time too many (or one time too
few). (
http://web-books.com/MoBio/Free/Ch7F3.htm ) So in this case, we would count the father's repeats, and say he
had 11 repeats of TCTA in DYS391, and his score on that marker is 11.
However, if one of his sons had 12 TCTA repeats, his son would have a marker
score of 12.
TTCAATCATACACCCATATCTGTCTGTCTG/TCTA/TCTA/TCTA/TCTA/TCTA/ TCTA/TCTA/TCTA/TCTA/TCTA/TCTA/TCTGCCTATCTGCCTGCCTACCTAT CCCTCTATC |
If a father had 6 sons, perhaps 5 of his sons would inherit the DYS391=11
that he had, but one son might inherit 12 in the way that I have described
above. All of the other markers tested might have identical values
for all 6 sons. This means in 10 generations time, the chances are that the descendants of
the 5 sons with a value of DYS391=11, will still probably have a value of 11, but the
descendants of the son with a value of 12 will probably have a value of 12 for that
marker. This means that by testing a males Y-DNA, and seeing what values he has for
the markers, sometimes it is possible to predict where he might be related on a particular
family tree, particularly if he has some distinctive markers which only occur in one
branch of the family. If we get lucky, sometimes we might be able to
say that a person is probably descended from an identified ancestor living
hundreds of years ago. In the Marsh project, we have be able to tell a
number of participants that they likely descend from particular Marsh
pioneers in USA in the 1600s. When we have sufficient participants
from different branches of families, we should be able to identify specific
branches which Marshes are likely to have come from.
With a Y-DNA test, if two males matched on 25 of 25 markers, it does not
"prove"
they are closely related, but it does indicate that it is "very likely". We look for
corroborating evidence to support matching DNA results, and if the 2 males had the same
surname, and traced their ancestors back to the same village, it clearly increases the
likelihood of them being relatively closely related. If two males of the same
surname matched on only 10 of 25 markers, it would be considered conclusive evidence that
the two were not closely related on the direct male line, and their most
recent common direct male
line ancestor might have been many thousands of years ago. Statisticians have of formulas
for estimating probabilities of how many generations back to a Most Recent Common Ancestor
("MRCA"), for different numbers of matches on markers.
The goal of the Marsh Families DNA Project is to test as many Marsh males as possible
from as many different families and locations as possible, and build up over time a
database of different Marsh family Y-DNA profiles. Ideally for very large Marsh families,
4 or more separate remote branches of the family should be tested, to get a better
indication of what the ancestral Y-DNA profile would have been. If only one branch is
tested, it could be the only branch that has mutations on it, and it might give a
misleading indication of the probable ancestral Y-DNA for that family. As this database
builds up, it will become a valuable tool for genealogists, and help Marshes around the
World to gain clues to their ancestral origins, and possibly find long lost branches of
their families. In the Marsh DNA project so far, we have linked a
number of Marshes to their ancestry, confirmed suspected ancestries in some
cases, and linked Marshes to their lost lines of cousins.
A secondary goal for participants in this project, would be the chance to learn
something of their "deep ancestry". By this I mean indications of the
broad tribal origins they stem from in the direct male line, over the past tens of
thousands of years. The genetic scientists have developed basically a family tree of
mankind, which identifies different "haplogroups", which are related groupings,
and this enables us to identify the corner of the big picture that we individually fit
into. (see
http://isogg.org/tree/ &
http://www.familytreedna.com/haplotree.html.) Working from the "haplotree", and distribution
patterns of person of similar haplotypes, it is possible to in general terms plot the
trail of our ancestors out of Africa, up to the last Ice Age, and sometimes get
indications on the ancestral trail over the years since the Ice Age. On the results
page at http://marshdna.arrrg.org/DNAresults.htm
has been included a tree of all Marsh families identified in the Marsh DNA Project,
and shows their approximate deep ancestry linkages, and the migration trails over the millennia.
5) FREQUENTLY ASKED QUESTIONS:
The Project Administrator of the Marsh Families DNA Project, is using Y-DNA test results
to attempt to trace relationships between various
Marsh families around the World, and to trace deep ancestry origins. The Project Administrator is not an
"expert" on all aspects of DNA, or Y-DNA, which are rapidly advancing
areas of science. For anyone interested in more background information on the parts
of DNA typically used in genealogy, it is suggested the "Frequently Asked
Questions" sections of DNA Test Company web sites, and other related sites, may
be helpful. See the following...
http://www.familytreedna.com/faq.html
(Family Tree DNA- FAQs) http://www.dnaheritage.com/faqs.asp
(DNA Heritage- FAQs)
http://www.dna-fingerprint.com/modules.php?op=modload&name=FAQ&file=index
(DNA Fingerprint- FAQs)
http://www.le.ac.uk/genetics/maj4/SurnamesFAQ041008.html
(Dr Mark Jopling, Leicester University)
Sorenson Molecular Genealogy Foundation (SMGF)
were offering free tests in their research project, and are investigating Y-DNA and mtDNA as used by most commercial test labs, but they
are also looking at additional parts of the DNA to learn about genealogical relationships.
For information more specific to SMGF see the following...
http://smgf.org/faq.html (Sorenson Molecular
Genealogy Foundation- FAQs)
6) REFERENCE INFORMATION ON DNA:
There is a huge amount of information on the internet about DNA testing in relation to
Surname Study Projects, such as this Marsh study. Following I have listed sites with
general reference information on various aspects of Y-DNA. I have roughly divided
these links up under topic headings.
Participants in the Marsh DNA Project don't need to know about the
"technical" side of DNA, but for those who are interested to know how it all
works, they can have a look around the following sites. The information may seem
bewildering, but once a person has been tested, and knows something about their
own DNA, it
makes it easier to make sense of the reference material. If you know what your Y-DNA
is, you can look for information specifically relating to you own Y-DNA, and you don't
have to be confused by volumes of information irrelevant to your own case.
If anybody has been looking through the following sites, and don't understand
something,
please contact the Project Administrator. He may be able to answer your query, or at
least know where to look for an answer.
DNA Task Force Flier/ DNA Articles etc:
http://www.dnalist.net/Flyer/index.html
*****
http://www.genealogydna.org/speakerslist
(DNA Task Force Speakers List)
http://www.newstimeslive.com/news/story.php?id=1009519 (National
Geographic DNA Project)
http://freepages.family.rootsweb.ancestry.com/~bonsteinandgilpin/
(A useful introduction to genetic genealogy from one surname project web
site)*****
DNA Web Pages-
general explanations about DNA, and giving references to useful DNA links:
http://worldfamilies.net/helpful_tools.htm
(DNA helpful tools) ***
http://www.isogg.org/ Internationsal Society of Genetic Genealogists web site
http://www.isogg.org/tree/ISOGG_Glossary08.html (Glossary of
Genetic Terms)
http://www.isogg.org/newsarchives.htm (ISOGG DNA News Archives)
*****
http://www.genetealogy.com/articles/html/
(Links to DNA articles on various topics)
http://vetinarilord.blogspot.com/
(DNA articles on various topics- good site)***
http://freepages.genealogy.rootsweb.com/~ncscotts/
(Scott
DNA site- excellent)******
http://www.contexo.info/DNA_Basics/Meiosis.htm
(Basic
biology for genetic genealogy)
http://learn.genetics.utah.edu/units/basics/index.cfm (DNA basics
and beyond)
http://freepages.family.rootsweb.ancestry.com/~bonsteinandgilpin/
(A useful introduction to genetic genealogy from one surname project web
site)*****
http://genealogy.about.com/cs/geneticgenealogy/a/dna_tests.htm
(Tracing your ancestry through DNA)
http://www.kerchner.com/dna-info.htm
(Kercher web page- General DNA reference material)
http://freepages.genealogy.rootsweb.com/~allpoms/genetics.html
(Pomery's DNA site)
http://blairgenealogy.com/dna/dna101.html
(Blairs DNA 101)*
http://www.familytreedna.com/dna101.html
(FTDNA DNA 101)* http://www.historicalgenetics.com/ (Historical
Genetics) http://gslc.genetics.utah.edu/units/basics/tour/
http://www.dnaheritage.com/tutorial1.asp
http://freepages.genealogy.rootsweb.com/~gkbopp/DNA/DNAtimeline.htm
(DNA historical time line of events)
http://worldfamilies.net/helpful_tools.htm
(Helpful Tools) http://worldfamilies.net/y-haplogroups.htm
(Y-Haplogroups) http://worldfamilies.net/mtDNA.htm
(mtDNA) http://worldfamilies.net/regional_project.htm
(Geographical Projects)
http://www.chezmaya.com/divers/moving.htm
(What Y-DNA looks like)
http://www.ancestry.com/learn/library/article.aspx?article=9816
(Genetic genealogy- survey)
http://freepages.genealogy.rootsweb.com/~geneticgenealogy/
(eclectic collection of DNA links-Little)
http://www.dnafiles.org/resources/index.html (Miscellaneous information
about DNA, not specifically about genealogical use of DNA)
http://www.smgf.org/resources/papers/PosterASHG2003.pdf (Pilot
project showing how autosomal DNA can be used in genealogy)
DNA Surname Projects being carried out:
http://www.worldfamilies.net/ (World
Families Network- comprehensive DNA project list)
http://www.dnalist.net/ (DNA surname projects)
http://www.duerinck.com/surname.html
(Duerinck webpage- gives a list of surname projects being
done) http://www.le.ac.uk/genetics/maj4/surnames.html
(Research project on surnames & DNA)
DNA Test Companies:
http://dna.woodruffgenealogy.net/ydnacomp.htm (Test company
comparison chart)*****
http://spreadsheets.google.com/pub?key=pUnr6rAB3u4lLJBq9_6t1Uw
(Test company calibration adjustments)*****
http://dgmweb.net/genealogy/DNA/ConversionFactors.shtml
http://www.genetealogy.com/resources/html/cat11.html
(List
of main test companies)
http://dnaconsultants.com/dna_tests/index.html?gclid=COaDx8CV-Y4CFQSOggod63Tv3g
(DNA Consulting)
http://freepages.genealogy.rootsweb.com/~bonsteinandgilpin/dna/ydnaco.htm
(List of markers tested by various companies)
http://www.thegeneticgenealogist.com/comparison.htm).2
(Comparisons of many of the genealogical DNA testing companies, note prices
given for some companies don't include sizable discounts offered to surname
projects being don't through those companies.)
http://www.thegeneticgenealogist.com/markerlist.htm).Blaine
(Comparison of markers tested by different test companies.)
www.familytreedna.com
or www.familytreedna.co.uk (Family Tree DNA)***
http://www.igenea.com/genealogy-dna-result-certificate-ancestry-07.htm
(iGENEA) (A company with a wide range of DNA services, good resources to assist customers, and a
very good reputation for customer services. See
http://www.ftdna.com/sitemap.html for FTDNA web site map. Note FTDNA invite interested genealogists
to subscribe to their free DNA newsletter. For anyone considering whether DNA has
any use in genealogy, this newsletter/ magazine is a good way to get monthly updates and
information on the use of DNA in genealogy... see
http://www.familytreeDNA.com/fgregister.asp
Past issues of the newsletter can be seen at
http://www.familytreeDNA.com/facts_genes.asp?act=past
Several have been intrigued by the report on the Meates project in the past issue
of the magazine at the following link, this dramatically shows how DNA can be used in
genealogy...
Facts & Genes
Volume 3, Issue 6, October 21, 2004 ***)
http://www.dna-fingerprint.com/static/FTDNA-Conference-2007-WalkOnY.pdf
(FTDNA Walk on Y Project)
http://www.igenea.com/index.php?content=31&test=y-12-group (FTDNA
Swiss Office)
http://online.wsj.com/public/article/SB119509026198193566.html
(African DNA) http://www.dnaheritage.com/
(DNA Heritage)***

http://www.relativegenetics.com/index.jsp
http://66.235.201.45:8085/relativegenetics
/ (Relative Genetics)*
http://www.cambridgedna.com
(Cambridge DNA- Cambridge DNA Services offers autosomal DNA ("admixture"),
mtDNA ("motherline"), and Y-DNA ("fatherline") tests for use in personal
ancestry research.)
http://www.tracegenetics.com/services_gene.html
(Trace Genetics- has large Native American database)
http://www.tracegenetics.com/services_gene.html#WYSNP
(SNP tests) http://www.ancestrybydna.com/
(Ethinic Composition) http://africanancestry.com/ (African
Ancestry) http://www.vita-med.com/ancientdna.cfm
(Remains Testing) http://www.geogene.com/index.htm
(GeoGene) http://beta.genetrack.com/index.php
(Genetrack) http://www.oxfordancestors.com/
(Oxford Ancestors)
http://www.rootsforreal.com/english/eng-home.html
(Roots For Real- MtDNA only?))
http://www.0800-gentest.de/ (biotix GmbH-
Germany) http://www.genbygen.de/genealogie_genotypisierung.htm
(GenByGen- Germany)
http://smgf.org/page.jspx?name=participate
Participating for FREE
in the Sorenson Molecular Genealogy Foundation DNA research project would assist the Marsh
Families DNA Project: (Sorenson research project- not strictly a test
company, but is offering free tests in a research project. Results are are not
directly given to participants, but there are ways they can be obtained. Contact
John Marsh for suggestions about how to obtain results. I recommend that all male
Marshes consider being tested. In the long run, it would be a huge help to the Marsh DNA
Project to have a wide range of Marshes tested. Please tell John Marsh if you are
tested in the Sorenson research project, as it will make it easier to locate results, if
it is known who has been tested. The free tests will not be offered indefinitely, so
if you are interested, take your chance while it is there. Being a research project,
they are doing a wider range of tests than commercial test labs, so it may be that we
learn some remarkable things not obtainable from other sources.)
http://www.businesswire.com/portal/site/google/index.jsp?ndmViewId=news_view&newsId=20080120005047&newsLang=en
((( Sorenson obituary)))
http://www.smgf.org/pages/smgf_genetree.jspx (relevant in relation
to SMGF above)
http://dnawitness.net (Ancestry by DNA)
http://www.ancientdna.com/ (Ancient DNA,
not structured for normal genealogical DNA testing, but may be useful trying to recover
DNA from artifacts belonging to deceased ancestors.)
http://www.biotix.de/index.php?newlang=eng
(Biotix, German company, ... offering some good services, renamed DNA Fingerprint, see new
contact details below) http://www.dna-fingerprint.com
(DNA Fingerprint, new name for biotix)*****
http://www.isogg.org/extractionchart.htm (DNA extraction from
personal effects, hair, stamps etc)
http://www.ethnoancestry.com/
(Ethnoancestry)*****
https://www5.nationalgeographic.com/genographic/
(National Geographic Genographic Project- not strictly a test company, and the results are
not primarily designed for "genealogical" purposes. However, anyone with
results from the Genographic Project will be able to use their results to get some
comparison to Marshes tested in the Marsh DNA Project. Any Marsh tested in the
Geonographic project is invited to contact John Marsh
ajmarsh@arrrg.org,
for assistance with comparing to Marshes in the Marsh Families DNA Project.)
http://www.ftdna.com/ftdna_genographic.html
(FTDNA site, comments re National Geographic Project)
http://www.clanlindsay.com/new_page_4.htm (List of markers tested by test companies)
http://www.chromosomal-labs.com (Chromosomal Laboratories)
www.dnatribes.com
www.healthanddna.com/genealogy.html
(Genelex)
http://www.genebase.com/
http://www.genebase.com/blog/?p=62 (Genebase markers) http://www.preventiongenetics.com/ (Method for good quality long
term DNA storage.)***
http://dnaaction.com/usa/dna-preservation.asp (DNA Preservation
Service)
http://www.dnaancestryproject.com/ydna_intro_howto.php
http://www.argusbio.com/about_us.html?osCsid=205c1c824eb40df4f7f09ae7d51a59d1
(Argusbio)
http://www.genetictechnologies.com.au/index_general.asp?menuid=040.010
(Australian DNA tests) http://www.familygenetics.co.uk/
(Family Genetics)
http://www.whatman.com/products/?pageID=7.31.31 (DNA storage
cards)*****
http://www.preventiongenetics.com/resgeno/researchgeno.htm (Specialist
types of DNA testing etc)
http://www.eyeondna.com/2007/06/21/dna-testing-in-the-czech-republic/
(Czech DNA companies- prices in the article are misleading, it seems only 12
markers are tested, and services are limited.)
http://money.cnn.com/news/newsfeeds/articles/prnewswire/NYF01016112007-1.htm
(deCODEme- to test 1 million base sections of DNA for SNPs)
http://www.decodeme.com/ (deCODEme)
{{http://members.aol.com/dnacousins/deCODEme_Compare_Genomes.zip
deCODEme comparisons example}}
http://www.rootstelevision.com/players/player_dna.php?bctid=1351299777
(explanation of deCODEme test)
https://www.23andme.com/ourservice/ancestry/science/ (23andme)
http://dnacousins.com/SNPs_on_Chips.xls
http://www.techcrunch.com/2008/03/02/my-23andme-dna-results/
(example of 23andme results)
https://www.23andme.com/user/signup/ (demo account for
23andme)
http://www.knome.com/ (Full
genome sequencing)
http://www.genomics.org.cn/bgi/english/index.htm# (Beijing
Genomics Institute)
http://www.familybuilder.com/
(Test company, new, but test prices look very competitive) *****
http://www.geni.com/
http://www.nytimes.com/2008/10/06/business/06gene.html?_r=1&ref=business&oref=slogin
(Low Price full Genome DNA sequencing technologies.)
http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=ind_focus.story&STORY=/www/story/11-03-2008/0004916773&EDATE=MON+Nov+03+2008,+06:05+AM
(full gennome sequencing)
Genealogical DNA testing
available in Johannesburg, South Africa:
PO Box 1038, Human Genomic Diversity and Disease Unit, School of
Pathology, Wits, NHLS, Johannesburg, South Africa, 2000
DNA Storage:
Since I have been running the Marsh DNA Project, I have been contacted
by a number of Marsh descendants who have no male line relatives living.
In some cases, the last male line relative had recently died, and the
options for getting samples for DNA testing are no longer available. I
suggest that if there is a single direct male line Marsh relative in
your family, that you might consider finding a way to get DNA stored for
testing in the future. If they are very elderly, it might also
suggest obtaining DNA samples should be considered in the near future.
Most test companies store DNA for free, itfa test is purchased from
their company. Some will process and store DNA for a relatively
small fee. An alternative is also simple storage kits which can be
purchased to enable DNA of relatives to be stored in your own home, so
that you have freedom to get testing done at any test company in the
future. As DNA science is rapidly advancing, who can say the
exciting opportunities we may have in the future, for learning about our
family origins with DNA. If DNA is stored, it is a cheap insurance
policy which enable future testing.
http://www.thegeneticgenealogist.com/2007/08/28/dna-from-the-dead-dna-banking-is-legal-but-is-it-ethical-part-i/
(DNA Storage)
http://www.preventiongenetics.com/ (Method for good quality long
term DNA storage.)***
http://dnaaction.com/usa/dna-preservation.asp (DNA Preservation
Service)
http://preventiongenetics.com/
(DNA Storage using Blood)
http://www.thegeneticgenealogist.com/?s=DNA+Banking&x=15&y=8 (DNA
Banking)
http://www.dnadirect.com/patients/tests/dna_archive_storage/index.jsp
(DNA Direct home storage system for DNA)
http://archiver.rootsweb.com/th/read/genealogy-dna/2007-04/1177326061
(Discussion of FTA cards)
http://archiver.rootsweb.com/th/read/genealogy-dna/2007-04/1177326061
(Comparing DNA storage systems)
http://www.whatman.com/FTANucleicAcidCollectionStorageandPurification.aspx
DNA Consultants & related services:
http://www.isogg.org/consult.htm
(DNA Consultants & related services)
DNA accessories:
http://www.dnapin.com/ (If you have been
DNA tested, and have learned which DNA "haplogroup" you are a member of, you can
purchase pins to wear which show your haplogroup)
http://home.comcast.net/~libpjr1/dnapins.htm
(Haplogroup pins etc.)
http://www.dna-fingerprint.com/modules.php?op=modload&name=Downloads&file=index&req=viewdownload&cid=2
(Omnipop spreadsheet.) http://www.dna-rainbow.org/ ("DNA
rainbow" perhaps interesting, but not strictly useful for genealogy)
Glossary of DNA terms:
http://www.kerchner.com/dna-info.htm
(Glossary, use "Genetic Genalogy Glossary" link second line on page)
http://edmund-rice.org/dnagloss.htm
(Glossary of DNA terms)
http://www.contexo.info/DYSYCAII.htm
(Technical information.)
http://www.genomatix.de/online_help/help/sequence_formats.html
(DNA Sequence formats)
DNA is cost effective research:
http://www.familytreeDNA.com/facts_genes.asp?act=show&nk=2.9
(DNA costs compared to alternatives)
Interpretation of results:
http://www.davidkfaux.org/dnaprofile2
(example of one person's interpretation of his results for haplotype R1b)
About Haplogroups:
http://www.kerchner.com/haplogroups-ydna.htm (Haplogroup descriptions)
http://www.familytreedna.com/PDF/2008-HaploChart_GR_lores.pdf
***** (Haplotree-FTDNA)
http://isogg.org/tree/ (Haplotree...
note there are different versions) *****
(Haplotree-ISOGG)
http://dna-forums.org/index.php?showtopic=1274&hl= (Y-DNA Haplotree)
http://www.eupedia.com/europe/origins_haplogroups_europe.shtml#R1b
http://dgmweb.net/genealogy/DNA/SNPcharts/R1b_2009-03-19.shtml
(Haplotree comparisons)
http://www-ab.informatik.uni-tuebingen.de/software/dendroscope/welcome.html
(Phylogenic tree software- free) {{note see
http://www.vizachero.com/R1b1/R1bSplits.png for an example of a
network tree using this software... the suggestion is the software is
easy to use.}}
http://nexus.ugent.be/geert/
(Tree illustrator)
http://splitstree.org/
(Phylogenic tree software- free)
http://members.bex.net/jtcullen515/HaploTest.htm
http://www.worldfamilies.net/y-haplogroups.htm
(Haplogroups)
http://www.eupedia.com/europe/origins_haplogroups_europe.shtml
(age of haplogroups)?????
http://www.hprg.com/hapest5/ (Haplogroup predictor
programme)******
http://freepages.genealogy.rootsweb.com/~geneticgenealogy/ (useful
information about haplogroup, clustering, markers etc)****
http://freepages.genealogy.rootsweb.com/~dgarvey/DNA/RelGen/Butler_YCC_samples.htm (Typical haplotypes representing haplogroups)
http://members.bex.net/jtcullen515/temptable.html (Modal
Haplotypes for Haplogroups)
http://ycc.biosci.arizona.edu/nomenclature_system/table1.html
(Geographic/ Ethnic origins of haplogroups)
http://www.scs.uiuc.edu/~mcdonald/WorldHaplogroupsMaps.pdf (Y-haplogroups of Europe, distibution map)
http://freepages.genealogy.rootsweb.com/~dgarvey/DNA/RelGenMarkers.htm
http://freepages.genealogy.rootsweb.com/~dgarvey/DNA/markers.htm
http://freepages.genealogy.rootsweb.com/~dgarvey/DNA/Underhill_2003.html
http://ycc.biosci.arizona.edu/nomenclature_system/frontpage.html
(Nomenclature System for Haplogroups)
http://freepages.genealogy.rootsweb.com/~dgarvey/DNA/RelGen/YCC.html
(New Haplogroup system)
http://www.le.ac.uk/genetics/maj4/JoblingTS.03.NRG.Review.pdf
(New Nomenclature for R1b Haoplogroup- GOOD)
http://www.maik.ru/eng/online/index.htm
(about haplogroup R1a in Eastern Europe)
http://baz.perlmonk.org/haplogroups.jpg
(Haplogroup map of Europe)
http://freepages.genealogy.rootsweb.com/~dgarvey/DNA/y_bosch.htm
(Modal STR alleles for haplogroups)
http://freepages.genealogy.rootsweb.com/~dgarvey/DNA/RelGen/YSTR.htm
(Modal STR alleles for haplogroups)
http://www.roperld.com/YBiallelicHaplogroups.htm
(Timetable of haplogroup markers- GOOD)
http://www.racearchives.com/calc/haplo_data.asp?dbname=ychroms
(Human races calculator- uses old haplogroup names)
http://ybase.org/statistics.asp
(Frequency of DYS nos, typical haplotypes within haplogroups)
http://smgf.org:8081/pubgen/site15.jsp
(Frequesncy of DYS numbers in Sorensen study etc)
http://www.familytreedna.com/pdf/ZeguraMBE2004.pdf
http://evolutsioon.ut.ee/publications/Cinnioglu2004.pdf
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=56946
http://hpgl.stanford.edu/publications/AJHG_2003_v72_p281-302.pdf
http://hpgl.stanford.edu/publications/HG_2000_v107_p582.pdf
http://www.journals.uchicago.edu/AJHG/journal/issues/v70n1/013099/013099.text.html
http://www.dienekes.com/blog/archives/000532.html
http://hpgl.stanford.edu/publications/AJHG_2001_v68_p432.pdf
http://www.journals.uchicago.edu/cgi-bin/embpcgi.pl/cgi-bin/res-page.epl?objid=316949
(Australian/ Melanesian)
www.cshl-symposium.org/doi/pdf/10.1101/sqb.2003.68.487 http://dienekes.blogspot.com/ (Includes
modal haplotypes for different regions)
http://www.geocities.com/prooferjoan/R1b.htm
(Common R1b haplotype distributions)
http://home.earthlink.net/~wilsondna/FILE_DOWNLOAD_PAGE.htm
(Includes file of R1b haplotypes)
http://www.geocities.com/mcewanjc/p3origin.htm
(Haplogroup distribution analysis by John McEwan- interesting)***
http://www.geocities.com/null439/Dist2.htm (Allele values in different
haplogroups)
http://freepages.genealogy.rootsweb.com/~ncscotts/Y-DNA/Oppenheimer%20Clan%20Test.htm
Oppenheimer Clan Test Results.
http://www.genebaze.cz/cgi-bin/ydmarmod.cgi?lang=us&n=cz (Modal
values Czech DNA Project)
https://www3.nationalgeographic.com/genographic/atlas.html (NG Atlas of
the human journey) http://www.ethnoancestry.com/info.html (Links to info on
haplogroups) http://www.kerchner.com/haplogroups-ydna.htm (Brief description of
haplogroup origins)
http://freepages.genealogy.rootsweb.com/~jswdna/haplogroupvalues.htm
(Modal haplotypes for haplogroups)
http://www.dna-fingerprint.com/user.php?op=userinfo&uname=HUGO (Hugo
reference sequence)
A
Haplogroup:
http://www.nature.com/ejhg/journal/v15/n3/abs/5201771a.html
B
Haplogroup:
C
Haplogroup:
E
Haplogroup:
http://www.haplozone.net/e3b/project/loadview/15
(E Haplogroup Modals)
http://www.haplozone.net/e3b/project
http://maps.google.com/maps/ms?ie=UTF8&hl=en&msa=0&msid=105754639437185730882.00044a5cd3d6919bb64a5&ll=39.504041,-12.832031&spn=28.784698,59.414063&t=p&z=4
(Distribution map of
E3b in Iberia)
http://dna-forums.org/index.php?showtopic=4327
F
Haplogroup:
http://www.familytreedna.com/public/F-YDNA/
G
Haplogroup:
http://www.members.cox.net/banksfamilies/67markernetwork.html
H
Haplogroup:
https://www.familytreedna.com/public/YHaploGroupH
I
Haplogroup:
www.northwestanalysis.net (I
haplogroup)
http://freepages.genealogy.rootsweb.com/~geneticgenealogy/I67y.gif
(I haplogroup clusters, 67 markers)
http://www.familytreedna.com/(voke2055jc3g2i55hm2yfbih)/public/yDNA_I1a/index.aspx
(I1a project)
http://www.familytreedna.com/public/I1b2HapGroup/index.aspx (I1b2
project)
http://tinyurl.com/2b76jd
(I1b2* project)
http://www.familytreedna.com/public/I1c-Y-Clan/index.aspx (I1c
project) http://docs.google.com/View?docid=dg8hv2jm_3d8qnqz
(Old
I1c)
http://listsearches.rootsweb.com/?list=Y-DNA-HAPLOGROUP-I (Y haplogroup
mailing list)
http://www.geocities.com/prooferjoan/I1a.htm
(Common I1a haplotype distributions)http://www.geocities.com/vetinarilord/hapi.pdf
(Haplogroup I- Rootsi study)
www.northwestanalysis.net (Haplogroup
I web page- Nordvelt)
http://www.gslt.hum.gu.se/~leifg/jh/ (I haplogroup analysis)
J
Haplogroup:
http://www.j2-ydnaproject.net/ie7.html
(J2 Project)
http://www.ftdna.com/pdf/HaploJ.pdf
(Haplogroup J study)
http://j1bm365.blogspot.com/
K
Haplogroup:
Q
Haplogroup:
http://www.familytreedna.com/(y5gvf13owg4upl45usam0q45)/public/yDNA_Q/index.aspx
(Q Haplogroup Project)
www.qydna.org
(Q Haplogroup Project)
http://www.qydna.org/g3yhrd.xhtml (Q haplogroup
results) Q Haplogroup modal haplotypes shown on Y-Search
are as follows... 2Q5V7 The Jewish (Ashkenazi) Y-DNA-Q modal haplotype. BE9R2 The Native American Y-DNA-Q modal haplotype. F5F44 The Old Norse Y-DNA-Q modal haplotype. THZ96 The Y-DNA-Q Security modal haplotype. (most Qs are within 3
steps of this haplotype)
http://www.freewebs.com/ydna_q/
(Q haplogroup project)
http://www.genebase.com/tutorial/item.php?tuId=16
(Haplogroup Q)
R
Haplogroup:
Note, the "naming" of subclades of R is
continually changing, and some of the headings below have been
superseded.
http://dgmweb.net/genealogy/DNA/SNPcharts/ISOGG-FTDNA_HapR_2009.shtml
http://www.eupedia.com/europe/origins_haplogroups_europe.shtml#R1b
R1a:
http://www.ncbi.nlm.nih.gov/pubmed/17534642?dopt=Abstract (Ancient
R1a)
R1b:
http://en.wikipedia.org/wiki/Haplogroup_R1b_(Y-DNA)#R1b1b2_.28formerly_R1b1c.29
http://www.familytreedna.com/ftLogin.asp?
http://maps.google.com/maps/ms?client=firefox-a&hl=en&ie=UTF8&msa=0&msid=102956803377716741902.000459f49b2bc2c3cc27e&z=4
(R-L21 distribution map)
http://www.familytreedna.com/public/R-L21 (R-L21 project)
http://maps.google.com/maps/ms?ie=UTF8&hl=en&msa=0&msid=105486162464464051410.00044e6a01e1a2a6e7068&ll=44.840291,4.570313&spn=39.989817,155.390625&t=p&z=2
(R-P312 distribution map)
f=112http://www.ethnoancestry.com/index_files/index_data/Haplogroup_R2_Manoukian.pdf
(R2)
http://dna-forums.org/index.php?showtopic=998&pid=12295&start=0&#entry12295
(Modal haplotypes for divisions within R1b1c on Y-Search)
http://www.geocities.com/mcewanjc/r1bsnp.htm (McEwan database
or R1b SNPs)
http://www.geocities.com/mcewanjc/p3modal.htm (McEwan database of
haplogroup modals etc.)
http://www.worldfamilies.net/SWAMH.html (Allele frequencies in R1b)
http://italydna.blogspot.com/2007/01/r1b-in-italy.html (R1b in
Italy)
http://www.familytreedna.com/(wxy4wl45wwghvnrvpqqu3u55)/public/r1b/index.aspx
(R1b Project)
http://www.familytreedna.com/public/r1b
http://freepages.genealogy.rootsweb.com/~geneticgenealogy/R1b67y.gif
(R1b haplogroup clusters 67 markers)
http://www.geocities.com/mcewanjc/p3modal.htm#_R1b_haplogroup:_subcluster_modal_ha
(Modal values for various haplogroups and haplogroup clades and clusters)***
www.northwestanalysis.net
(R1b Modals for varieties)
http://www.jogg.info/31/campbell.htm (Geographic patterns of R1b in
British Isles)
http://www.jogg.info/51/files/Wright.htm Irish type III R1bs
R1b1c
Irish type III cluster:
http://www.irishtype3dna.org/ (R1b1c Irish Type III cluster web site)
R1b1c4
Haplogroup:
http://www.geocities.com/mcewanjc/r1bsnp.htm
(Includes R1b1c4- a small group of 7 or
more R1b1c4 haplotypes are known)
R1b1c6
Haplogroup:
R1b1c7
Haplogroup:
http://www.familytreedna.com/public/R1b1c7 (R1b1c7 Project)
www.m222.net/R1b1c7 (R1b1c7 Project)
R1b1c9
Haplogroup:
http://freepages.genealogy.rootsweb.com/~geneticgenealogy/1313.htm
(Distribution map for part of R1b1c9)
http://members.aol.com/chantery/S29DNA/S29_2.html (R1b1c9b- S29)
http://www.geocities.com/mcewanjc/s21.htm
(SNP S21)
http://tech.groups.yahoo.com/group/R1b1c_U106-S21/
R1b1c10
Haplogroup:
http://www.vizachero.com/images/R1bClades.pdf
(Distribution maps for R1b1c6, 7, 9, & 10)
http://docs.google.com/View?docID=dg8hv2jm_35wgncgf&revision=_latest&pli=1
(R1b1c10)
http://www.davidkfaux.org/LaTene_Celt_R1b1c10.pdf (R1b1c10)
http://www.familytreedna.com/public/r1b1c10/ (R1b1c10)
http://www.cerbere.ca/S28/
(R1b1c10)
http://www.familytreedna.com/public/r1b1c10/ (R1b1c10 project)
http://docs.google.com/View?docID=dg8hv2jm_35wgncgf&revision=_latest
(R1b1c10)
R2
Haplogroup:
http://www.ethnoancestry.com/index_files/index_data/Haplogroup_R2_Manoukian.pdf
SNPs: (SNPs are very slow mutating markers which are
used to define haplogroups. It is supposed that most SNPs
have mutated only once in the whole of human history, meaning that all descendants of the
ancestor who had that SNP mutation, will also have the mutation, but no others will have
it.)
http://hpgl.stanford.edu/publications/NG_2000_167_Y_Markers.doc
(SNP tables with tech info)
http://freepages.genealogy.rootsweb.com/~dgarvey/DNA/RelGen/Butler_YCC_samples.htm
('20 Marker haplotypes for worldwide YCC samples')
http://www.dna-fingerprint.com/static/FTDNA-Conference-2007-WalkOnY.pdf
(Search for Y SNPs- presentation at FTDNA conference 2007)
http://www.cstl.nist.gov/biotech/strbase/pub_pres/Butler2003b.pdf
(STR & SNPs Butler article)
http://isogg.org/tree/ISOGG_YDNA_SNP_Index.html (ISOGG Y-DNA SNP List)
http://groups.yahoo.com/group/DNA-ANTHROGENEALOGY/database?method=reportRows&tbl=3
(SNP Names database)
http://archiver.rootsweb.com/th/read/GENEALOGY-DNA/2006-01/1137428043
(Simple technical description of a SNP)
http://www.ncbi.nlm.nih.gov/projects/SNP/ (Database where SNPs are
recorded) http://www.allsnps.com/snpbrowser (SNP browser- it has been
suggested using a firewall on this site.)
http://www.davidkfaux.org/dnaprofile2.html (Speculated origins of
a family with SNP S28+)
http://home.cfl.rr.com/wade3/S21%20and%20R1b%20group%20compared%20081206.xls
(S21+ modals)
http://www.snp-y.org/ (SNP-Y
Database)
STRs: (STRs are the DNA markers which are mostly tested in
surname projects.)
http://spreadsheets.google.com/pub?key=pUnr6rAB3u4lLJBq9_6t1Uw
(Test company calibration adjustments)*****
http://www.cstl.nist.gov/biotech/strbase/STRseq.htm (Sequencing of
unusual STRs)*****
http://www.dna-fingerprint.com/modules.php?op=modload&name=Downloads&file=index&req=viewdownload&cid=2
(several useful tools, including marker distributions around the World, and Palindromic
region diagrams)
http://www.cstl.nist.gov/div831/strbase/pub_pres/ISFG_%20Y-STRupdate.pdf
(220 potentially useful Y-DNA markers) *****
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1794629&rendertype=table&id=Tab2
(Variation of 50 new STRs) *****
http://www.answers.com/topic/list-of-dys-markers
(list of STR
markers)
http://www.cstl.nist.gov/biotech/strbase/pub_pres/NIJposter2007_newLoci.pdf
(List of diversity of 82 markers)
http://www.kerchner.com/r1bproject/cssmarkerstats/charts.htm
(Frequency of STR allele values in R1b)*****
Haplotree etc: (Note, this seems to be modified over
time, particularly for subclades) http://isogg.org/tree/ (ISOGG
Haplotree)
http://www.familytreedna.com/haplotree.htm
(Haplotree)
http://www.le.ac.uk/genetics/maj4/JoblingTS.03.NRG.Review.pdf
(Includes Haplotree- takes a while to download)
http://www.rafonda.com/age.html (Age
and origin of the human species)
http://ycc.biosci.arizona.edu/nomenclature_system/frontpage.html
(Y chromosome consortium web site)
http://www.fluxus-engineering.com
(Phylogenetic genetic chart software)
http://www.cstl.nist.gov/biotech/strbase/pub_pres/Vallone2004a.pdf
(Haplotree)
Genetic distance:
http://nitro.biosci.arizona.edu/ftDNA/Distance.html#Step
http://freepages.genealogy.rootsweb.com/~gkbopp/KINNEY/Research/gendistance.htm (Genetic distance)
http://www.mymcgee.com/tools/index.html
(Software to produce a table to compare genetic distance)
http://www.familytreedna.com/GDRules_37.html
(37 markers, interpreting "relatedness" from genetic distance)
http://www.mymcgee.com/tools/index.html
(Genetic distance grid software)
http://www.mymcgee.com/results.html#geneticdistance
(Genetic distance calculator)
ASD:
http://dna-forums.org/index.php?showtopic=343&hl= (37 marker ASD calculator)
http://users.telenet.be/callmewimpy/67ASD.xls (67 marker ASD
calculator)
http://users.telenet.be/callmewimpy/links.htm (ASD
calculator on this web site)
Mutation rates: (see also at the very
bottom of this page) http://worldfamilies.net/marker.htm
(Mutation rate data)*****
http://www.worldfamilies.net/marker.htm
http://hpgl.stanford.edu/publications/AJHG_2004_v74_p000-000.pdf
(technical article)
http://www.journals.uchicago.edu/cgi-bin/resolve?AJHG991495PDF
(Mutation study, father son pairs. by Kayser)
http://www.kerchner.com/dnamutationrates.htm
(Mutation rate overview)
http://www.kerchner.com/cgi-kerchner/ystrmutationrate.cgi
(Mutation rate log)
http://searches2.rootsweb.com/cgi-bin/ifetch2?/u1/textindices/G/GENEALOGY-DNA+2005+548812243546+F
(Mutation rates- Chandler)
Time to "Most Recent Common Ancestor" (MRCA)
# NOTE: all of the following give very approximate assessments, because
variables such as what generation time you chose to apply, what average mutation rate you
use, and whether "fast" or "slow" markers mutate, has a big bearing on
"conclusions". Even then, the "possibility range" will encompass
a very large time frame between 5% and 95% probability expectations. Sometimes
one or two known facts can greatly narrow down the range of possibilities. The
pattern of which markers have mutated in comparrison to other family members is a big
help. That is why the more family members tested, particularly distant cousins,
makes it easier to interpret results. TMRCA calculations taken alone for comparing
two individuals should not be taken too seriously. They do have a value when
considered in conjunction with other evidence.
http://nitro.biosci.arizona.edu/ftdna/TMRCA.htm
http://members.aol.com/dnafiler/MutationCalculator.exe
(Anne Turner's Time to MRCA calculator)*****
http://dna-project.clan-donald-usa.org/tmrca.htm (TMRCA
Calculator)
http://www.bearport.org/Downloads/MRCAChart-b.4.zip
(alternative Time to MRCA calculator)
http://blairgenealogy.com/dna/markers.html
(Marker analysis)***
http://blairgenealogy.com/dna/FTDNATiP.html http://nitro.biosci.arizona.edu/ftDNA/Distance.html
(Genetic distance calculations)
http://www.cottrellweb.com/dna/mrca-12.htm
(probabilies re TMRCA for 12 markers)
http://www.cottrellweb.com/dna/mrca-25.htm
(probabilies re TMRCA for 25 markers)
http://www.cottrellweb.com/dna/mrca-37.htm
(probabilies re TMRCA for 37 markers)
http://www.cottrellweb.com/dna/mrca-43.htm
(probabilies re TMRCA for 43 markers)
www.moseswalker.com/mrca/calculator.asp
(MRCA calculator)
http://www.moseswalker.com/mrca/calculator.asp?q=1 (MRCA calculator)
http://www.bartondna.info/Software/MRCAChart-b.4.zip (MRCA calculator)
http://www.genetics.org/cgi/reprint/158/2/897.pdf (Estimating
TMRCA, technical article, Walsh)
http://users.telenet.be/callmewimpy/TMRCA-Calculator.xls (TMRCA
calculator)
http://dna-project.clan-donald-usa.org/tmrca.htm
(TMRCA calculator-McDonald)*****
DNA evidence of migration events/ Ethnic genealogy/ Regional
distribution of haplogroups etc:
http://vetinarilord.blogspot.com/
(Using genetic research to follow human migration patterns.)
https://www3.nationalgeographic.com/genographic/atlas.html
(National Geographic Human Migration Maps- with video)
http://mappemonde.mgm.fr/num11/articles/art06306.html (Map with
distribution of populations in Europe during last Ice Age)
http://my.opera.com/macedonians/blog/2008/01/29/the-late-glacial-ancestry-of-europeans
(The Late Glacial ancestry of Europeans: Combining genetic
and archaeological evidence)
http://arheologija.ff.uni-lj.si/documenta/pdf33/gamble33.pdf (Late
Glacial ancestry of Europeans)
http://www.eurekalert.org/pub_releases/2008-02/plos-hin021108.php
(Ancient migration to America)
http://class.csuhayward.edu/faculty/gmiller/3710/dnarefs.html
(Ancestral DNA references)
http://www.bbc.co.uk/history/programmes/bloodofthevikings/genetics_results_01.shtml
(Viking genetic survey results)
http://mbe.oupjournals.org/cgi/content/full/19/7/1008
(Y Chromosome Evidence for Anglo-Saxon Mass Migration)
http://thescotsman.scotsman.com/index.cfm?id=1393742006 (Origins of
people of British Isles- Sykes)
http://www.davidkfaux.org/dnaprofile2z.html
(Y-DNA research articles/ Iceland/ Norway/ Anglo Saxon)
http://www.newswriting.net/ID82.htm
(Links to ethnic genealogy webs sites)
http://www.historicalgenetics.com/Clusters.html
(regional distribution study of specific markers)
http://www.le.ac.uk/genetics/maj4/JoblingTS.03.NRG.Review.pdf
(Includes regional distribution of haplogroups- takes a while to download)
http://www.davidkfaux.org/shetlandislandsY-DNA2Rev.html
(Shetland DNA study)
http://www.galwayadvertiser.ie/dws/story.tpl?inc=2005/03/17/news/56881.html<http://www.galwayadvertiser.ie/dws/story.tpl?inc=2005/03/17/news/56881.html
(Irish surnames DNA study)
http://ealerts.nature.com/cgi-bin24/DM/y/ebN50Sn1nD0Hh40BGQZ0EG (Scale
of Viking settlement of Ireland, based on Y-DNA study)
http://home.comcast.net/~libpjr1/bahamasdna.html
(Bahamas DNA Study)
http://www.davidkfaux.org/dnaprofile2z
(Articles- Celtic, Anglo - Saxon, Jute, Danish Viking, Norse Viking)
http://www.nature.com/ejhg/journal/vaop/ncurrent/extref/5201651x2.xls
(Y-DNA Sweden)
http://www.german-dna.net/
(German Heritage DNA) www.frenchdna.org (French DNA
Project)
http://www.familytreedna.com/public/WalesDNA/index.aspx (Welsh DNA
Project) http://www.familytreedna.com/public/benelux/ (Belgium/
Netherlands/ Luxemburg DNA)
http://news.bbc.co.uk/1/hi/wales/1256894.stm (Y-DNA link Celts, Irish,
and Basques)
http://dienekes.blogspot.com/2005/12/y-chromosomes-of-norway.html
(Y chromosome in Norway)
http://icliverpool.icnetwork.co.uk/0100news/0100regionalnews/content_objectid=13718050_method=full_siteid=50061_headline=-Viking-past-proved-by-new-tests-name_page.html
(Viking DNA)
http://www.nature.com/cgi-taf/DynaPage.taf?file=/hdy/journal/vaop/ncurrent/full/6800661a.html
(Viking DNA)
http://www.ftdna.com/public/vikingydna/
(Viking DNA Project)
www.brigadoon.net/scottishdna.htm (Scottish Clans DNA)
www.scottishdna.net (Scottish
Clans DNA) http://www.calabriadna.com (Calabrian DNA
study) http://www.greekdnaproject.net/ydna.gif (Greek DNA Project)
http://www.dnaheritage.com/masterclass2.asp
(Human migration maps)
http://www.familytreedna.com/DNAPrintRes/map.pdf
(Human migration routes)
http://news.nationalgeographic.com/news/2002/12/photogalleries/journey_of_man/popup2.html
(Migration roots)
http://news-info.wustl.edu/tips/page/normal/6349.html
(Out of 3x Africa theories)
http://www3.interscience.wiley.com/cgi-bin/fulltext/112221248/PDFSTART
(Out of 3x Africa theories full article)
http://hpgl.stanford.edu/publications/Examining_2003_chapter6.pdf.
("Inference of Neolithic Population Histories using Y-Chromosome
Haplotypes"- may take a while to download)
http://www.nottingham.ac.uk/~sczsteve/survey.htm
(Genetic Survey of Wirral and West Lancashire- Viking DNA)
http://www.broad.mit.edu/media/archive/pr_01_drlinkage.html
(SNP's and human population history)
http://www.eurekalert.org/pub_releases/2003-05/su-sud052703.php
(Population expansion Europe 25,000 years ago)
http://www.journals.uchicago.edu/cgi-bin/resolve?AJHG024787PDF
(Population expansion Europe 25,000 years ago)
http://news.bbc.co.uk/1/hi/uk/3618613.stm
(Openheimer theory- Anglo/ Scottish split)
http://www.newscientist.com/news/news.jsp?id=ns99994586
(not a DNA article, but covers past 40,000 in Europe)
http://www.sciencedaily.com/releases/2004/01/040122082842.htm
(Tracking human migration with DNA)
http://www.tracegenetics.com/Eshlemanetal2003.pdf
(Migration to the Americas)
http://www.familytreedna.com/pdf/ZeguraMBE2004.pdf
(Y chromosome of Native Americans)
http://freepages.genealogy.rootsweb.com/~dgarvey/DNA/Paracchini.htm
(Y-Haplogroups California/Hawaii)
http://www.bauuinstitute.com/Articles/JonesmtDNA.pdf
(Native American Demographic History & DNA)
http://www.ismmed.org/VWCMM_Abstracts_Late.htm
(Native American)
http://www.nature.com/cgi-taf/DynaPage.taf?file=/ejhg/journal/v11/n7/abs/5200992a.html
(Croatian Y-DNA)
http://anthro.palomar.edu/vary/vary_3.htm
(Map of blood group distribution- not DNA, but a related issue)
http://groups.yahoo.com/group/thelasticeage/
(Message group- humans during the last ice age) "In the Iberian Peninsula
it appears that only three haplogroups survived that harsh 2,000? year period about 20,000
years ago (Y-chromosome R1b and mtDNA V and H - Bryan Sykes' Velda and Helena).
The Italian and Balkan Peninsulas managed to only support Y-chromosome I and
mtDNA T and K (Tara and Katrine). The steppe to the east of the Black Sea was home to
Y-chromosome R1a and mtDNA X (Xenia which includes I - Bonnie Schrack's Iris). In the
Fertile Crescent of the Middle East lived Y-chromosome G and ? and mtDNA J (Jasmine) and ?
To learn more about this period in Europe and the rest of the world, I've started a a
collaborative project to provide Web resources about humans and their environment during
the Last Glacial Maximum."
http://www.pnas.org/cgi/reprint/98/1/22.pdf
(Genetics and the population history of Europe)
http://www.cohen-levi.org/jewish_genes_and_genealogy/jewish_genes.htm
(Cohen-Levi DNA, Jewish DNA study)
http://www.davidicdynasty.org/ (Davidic
Dynasty- DNA study)
http://news.yahoo.com/s/ap/20070705/ap_on_re_eu/hidden_holocaust
http://www.khazaria.com/genetics/abstracts-cohen-levite.html
(Jewish Genetics: Abstracts and Summaries)
http://www.journals.uchicago.edu/AJHG/journal/issues/v69n5/013033/013033.html
(Jewish DNA)
http://www.pnas.org/cgi/content/full/97/12/6769
(Jewish DNA) http://www.calvarysac.org/genetic.html (Judy
Siegel. _"Genetic link found among 'kohanim'.")
http://www.familytreedna.com/nature97385.html
("Y Chromosomes of Jewish Priests.")
www.gnxp.com/MT2/khazar.pdf
(Ashkenazi R1a results.) http://www.gnxp.com/MT2/khazar.pdf
(Ashkenazi/ Khazar)
http://home.earthlink.net/~djmill/fcdna.html"http://home.earthlink.net/~djmill/fcdna.html
(French Canadian DNA)
http://www.guardian.co.uk/comment/story/0,3604,926038,00.html
(DNA of black African Jews- Lemba tribe)
http://www.ucl.ac.uk/tcga/tcgapdf/Weale-HG-01-Armenia.pdf
(Armenian DNA)
http://archiver.rootsweb.com/th/read/GENEALOGY-DNA/2003-10/1065451895
(Distribution of haplotype I)
http://www.geocities.com/vetinarilord/hapi.pdf
(Haplogroup I)
http://www.historicalgenetics.com/Clusters.html
(Identification of population clusters using heirachical
clusters based on Y-STR distribution profiles)
http://africanancestry.com/ (African DNA)
http://www.comanchelodge.com/cherokee-blood.html
(Cherokee DNA studies/projects)
http://story.news.yahoo.com/news?tmpl=story&cid=585&e=1&u=/nm/20040906/sc_nm/science_migrations_dc
(First Americans from Australia?)
http://www.cbc.ca/stories/2003/10/28/inuit_blond031028
(Icelandic/ Inuit DNA)
http://www.lifesciencesnetwork.com/news-detail.asp?newsID=1381Icelandic
(Icelandic DNA, clues to human genetic code)
http://www.planetsave.com/ViewStory.asp?ID=2620
(History of Icelandic DNA project)
http://home.comcast.net/~libpjr1/haplogroupI.htm
(Haplogroup I & R1b- a description of origins)
http://www.racearchives.com/archived/archived.asp?sectionID=805965602398
(Human races archives)* # Note: examples of origins of haplogroups... Haplogroup is a ancestral
genetic population indicator:..e.g. R1b is from the European Atlantic Coastal area; R1a is
from the Russian Steppes; Q is Central Asian-Amerindian; G is a India, Pakistan; and H is
India, Sri Lanka, Pakistan. http://www.small-stuff.com/WELSH/ (Welsh
DNA Study)
http://www.familytreedna.com/public/WalesDNA/index.aspx (Welsh DNA
study)
http://freepages.genealogy.rootsweb.com/~wgeorge/dna/cornwall.html
(Cornish Y-DNA)
http://www.gen.tcd.ie/molpopgen/data.htm
(Irish DNA study)
http://www.familytreedna.com/pdf/Nature2000.pdf
(Y-DNA Ireland)
http://www.pnas.org/cgi/reprint/98/9/5078.pdf
(Y-DNA Ireland)
http://www.gen.tcd.ie/molpopgen/data.htm
(Irish DNA Study)
http://www.gen.tcd.ie/molpopgen/link%20files/McEvoy%20et%20al%202006%20Hum%20Gen%20Sup_Info.xls
(Irish families studied)
http://mbe.oupjournals.org/cgi/reprint/19/7/1008.pdf
(Y-DNA Ireland)
http://news.scotsman.com/scotland.cfm?id=51752005
(DNA ties of Scots to Iraq)
http://www.genetics.org/cgi/content/full/160/1/289
(Polynesan DNA)
http://www.pnas.org/cgi/content/full/97/15/8225
(Polynesan DNA)
http://hpgl.stanford.edu/publications/AJHG_2004_v74_p000-000.pdf
(re Poynesians & Gipsies)
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=31389
(Gypsy genetics)
http://www.cmj.hr/2005/46/4/16100752.pdf
(Croations.)
http://www.debradickerson.com/articles/identity_crisis.htm
(African DNA)
http://www.ocf.org/OrthodoxPage/reading/St.Pachomius/bede1_15.html
(Bede's description of distibution of Angles, Saxons, and Jutes in England, not re
DNA, but of interest in interpreting where DNA might have come from.)
http://www.stormfront.org/whitehistory/ychromo.htm
(Haplogroup trends in races/ geographic areas)
http://www.geocities.com/vetinarilord/basque1.pdf
(Basque Y-DNA)
http://www.familytreedna.com/public/Greece/
(Greek DNA)
http://www.gnxp.com/IndependentOriginsOfIndianCaster.pdf
(Indian Y-DNA)
http://dienekes.blogspot.com/2005/04/y-chromosome-lineages-from-portugal.html
(Portugal)
Human Genome/ Technical articles about Y-DNA/ DNA testing etc:
http://www.ensembl.org/Homo_sapiens/mapview
(information on the parts of the human genome)
http://www.ensembl.org/Homo_sapiens/mapview?chr=Y (Y-Chromosome
technical data)***
http://www.genome.gov/Pages/EducationKit/online.htm
(Human Genome research- includes animated tutorials)
http://jimwatsonsequence.cshl.edu/cgi-perl/gbrowse/jwsequence/
(James Watson Personal Genome sequence)
http://www.biomedcentral.com/news/20040527/01
(Chimpanzee DNA differs from Human)
http://archiver.rootsweb.com/th/read/GENEALOGY-DNA/2002-09/1032905676
(Chimpanzee Y-DNA)
http://www.nature.com/news/2005/050829/full/050829-9.html
(Full chimpanzee genome sequenced.)
http://www.nature.com/nsu/010215/010215-5.html
( "The Y Chromosome: Goldmine and Junkyard")
http://genome.ucsc.edu/cgi-bin/hgTracks?clade=vertebrate&org=Human&db=hg17&position=chrY&pix=620&hgsid=42345570&Submit=submit
(Human Genome Browser)
http://human.genelynx.org/cgi-bin/record?glid=24991
(Genelynx data)
http://www.nature.com/nature/focus/humangenome/
(re articles, human genome, at Nature>)
http://www.sanger.ac.uk/Info/Press/2004/041020.shtml
http://www.sciencedaily.com/releases/2005/03/050328174826.htm
(Human DNA & Primates)
http://www.cstl.nist.gov/div831/strbase/ystr_fact.htm
(Known Y-DNA STRs... DYS nos. etc.)
http://www.contexo.info/DYSYCAII.htm
(electropherograms etc.)***
http://www.dna-fingerprint.com/index.php?module=photoshare&func=showimages&fid=1
(electropherogram library)
http://www.heraldsun.news.com.au/common/story_page/0,5478,16163799%5E24331,00.html
(sequencing whole genome $3m.)
http://www.cstl.nist.gov/div831/strbase/pub_pres/ISFG_%20Y-STRupdate.pdf
(220 potentially useful Y-DNA markers)
http://www.nytimes.com/2005/01/16/health/16cnd-gene.html?ex=1106958798&ei=1&en=a59890bdf130f014
(Fertility- longevity)
http://www.opsi.gov.uk/acts/acts2004/20040030.htm (Human Tissue
Act) http://www.opsi.gov.uk/acts/acts2004/40030--d.htm#45
(Non-consensual analysis of DNA is at section 45)
http://www.time.com/time/magazine/article/0,9171,1541283-1,00.html (How
we became human)
http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=9786153 (Human
Genome database)
http://www.upi.com/NewsTrack/Science/2007/07/31/most_complete_primate_gene_study_reported/7928/
http://sciencenow.sciencemag.org/cgi/content/full/2007/730/4
http://www.ingentaconnect.com/content/bsc/jfo/2007/00000052/00000001/art00008
(DNA extraction from hair)
http://www.eurekalert.org/pub_releases/2007-12/pb-tip122707.php
(Human evolution & DNA)
http://arxiv.org/PS_cache/cond-mat/pdf/0601/0601394v2.pdf
(Future possibility for DNA testing whole genomes quickly)
http://www.dna-fingerprint.com/static/PalindromicRegion-V2.pdf (map
of palindromic region, relevant to RecLOH events)
http://www.technologyreview.com/Biotech/20640/ (Future
possibilities for cheap DNA testing)
http://www.foresight.org/nanodot/?p=2919 (Future
possibilities for cheap DNA testing)
http://scienceblogs.com/geneticfuture/2009/02/oxford_nanopore_making_progres.php
(High speed testing)
http://yh.genomics.org.cn/
DNA and historic figures:
http://www.isogg.org/famousdna.htm
(DNA database of famous people) ***
http://news.bbc.co.uk/2/hi/south_asia/7525060.stm (Yeti
DNA)
http://www.journals.uchicago.edu/cgi-bin/resolve?AJHG024530PDF
(article about Genghis Khan)
http://egweb.bcgsc.ca/journal_club/2003_2004/pdfs/short_report_031006_mongol_Y_chrom.pdf
(Mongolian DNA- Genghis Khan)
http://www.angelfire.com/va/TJTruth/
(Thomas Jefferson- there are many DNA articles on the net about Jefferson, his
Y-DNA was DYS19 = 15 DYS388 =12 DYS389-1 = 12 DYS389-2 = 27 DYS390
= 24 DYS391 = 10 DYS392 = 15 DYS393 = 13)
http://www.ysearch.org/lastname_view.asp?uid=&letter=&lastname=Devereaux&viewuid=PW3G7&p=0
(Historically the Devereaux family are believed to have the same Y-DNA origins as
William the Conqueror [from William's great uncle]. A DNA study has been started to
try and establish the ancestral Y-DNA of the Devereaux family. This result is for a
Devereaux who does not have a confirmed line back to William I's great uncle, but it
is a step towards identifying William's Y-DNA.)
http://dsc.discovery.com/news/briefs/20040119/columbus.html
(Christopher Colombus)
http://www.nytimes.com/2007/10/08/us/08columbus.html?_r=2&hp=&adxnnl=1&oref=slogin&adxnnlx=1191859208-WfbjoYGJiDXfns94DtOQog
(Christopher Colombus)
http://news.independent.co.uk/world/science_technology/story.jsp?story=6
(Christopher Colombus)
http://www.electricscotland.com/history/articles/norse.htm
(DNA of Somerled, Scottish clan chieftain circa 1100)
http://www.eurekalert.org/pub_releases/2006-01/uom-uom011706.php
(Abe Lincoln)
http://jimwatsonsequence.cshl.edu/cgi-perl/gbrowse/jwsequence/
(James Watson Personal Genome sequence)
http://dna-forums.org/index.php?showtopic=4389&hl= (DNA of
famous people)
Stories about how people have used DNA in genealogy:
http://www.richmond.com/locallife/output.cfm?ID=2777655&vertical=LocalLife
http://jgg-online.blogspot.com/
http://www.nytimes.com/2007/03/14/arts/14reun.html?_r=1&oref=slogin
(West family)
http://www.aconews.com/articles/2007/08/08/noc/news/news18.txt
(Berry family)
www.theday.com/re.aspx?re=e8a3a0de-cdd1-4059-9cca-401853e35927
http://www.timesonline.co.uk/tol/news/uk/science/article2753556.ece
http://www.nytimes.com/2006/01/22/weekinreview/22harmon.html?_r=1&n=Top/Reference/Times%20Topics/People/H/Harmon,%20Amy&pagewanted=all&oref=slogin
DNA from ancient sources:
NOTE: Paavo at the Max Planck institute in Germany is the
leader in this area now and he is making some exciting predictions.
http://dienekes.blogspot.com/2008/05/ancient-y-chromosome-studies.html
***
http://www.npr.org/templates/story/story.php?storyId=13890656&ft=1&f=1007
(Ancient DNA from spit)
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0002214#pone.0002214.s003
(ancient DNA 1000 to 2000 Years Old)
http://www.isogg.org/ancientdna.htm
(Ancient DNA)
http://dienekes.blogspot.com/2005/03/ancient-dna-compendium.html
(Ancient DNA Compendium)
http://www.donsmaps.com/index.html (Information about ancient
archaeology)
http://dsc.discovery.com/news/briefs/20040621/bison.html
(DNA from ancient hair- including Isaac Newton)
http://www.abc.net.au/science/news/stories/s1158845.htm
(Bronze age)
http://www.khaleejtimes.com/Displayarticle.asp?section=theuae&xfile=data/theuae/2004/december/theuae_december568.xml
(7,500 year old DNA)
http://www.cr.nps.gov/archeology/kennewick/kaestle.htm (Attempts
to get DNA from Kenwick Man)
http://www.archaeology.org/online/news/dna.html
(Neanderthal DNA)
http://www.msnbc.msn.com/id/13955661/from/ET/ (Full Neanderthal
DNA will be sequenced in 2 years)
http://www.sciencedaily.com/releases/2009/02/090212112731.htm (Draft
Neanderthal sequence completed)
http://www.sciencenews.org/view/generic/id/34990/title/Neandertal_mitochondrial_DNA_deciphered_
http://www.nature.com/nature/videoarchive/neanderthaldna (Video,
Neanderthal DNA)
http://ealerts.nature.com/cgi-bin24/DM/y/ebF10Sn1nD0HjB0BFjT0Ec
(Neanderthal)
http://arstechnica.com/journals/science.ars/2006/5/16/3992
(Neanderthal DNA)
http://www.wired.com/wired/archive/14.07/caveman.html (Neanderthal
DNA) http://www.isogg.org/neanderthaldna.htm (Neanderthal mtDNA)
http://www.archaeology.org/0611/abstracts/neanderthals.html
http://www.newscientist.com/article/dn10275-neanderthal-dna-illuminates-split-with-humans.html
(Neanderthal DNA)
http://www.nytimes.com/2007/10/02/science/02nean.html?_r=1&ref=science&oref=slogin
(Neanderthal DNA)
http://www.sciencemag.org/cgi/content/abstract/1147417 (Neanderthal
DNA suggests some had red hair and fair skin.)
http://abcnews.go.com/Technology/wireStory?id=689114
(400 year old Jamestown DNA sample)
http://www.nature.com/news/about/aboutus.html#Dalton
(10,000 year old American cave man DNA)
http://www.newscientist.com/article.ns?id=dn7988
(DNA from fossil bones.)
http://news.bbc.co.uk/1/hi/sci/tech/4260334.stm
(Extracting better quality DNA from ancient sources.)
http://www.everything2.com/index.pl?node_id=1476399 (mtDNA from Wales
24,000 years ago)
http://www.telegraph.co.uk/news/main.jhtml?xml=/news/2006/08/14/ndna14.xml
(DNA from 1000 year old Pict bones)
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=12858290
(2000 year old Egyin Gol DNA)
http://www.abc.net.au/science/news/stories/s1722109.htm (Suggestions
some human DNA comes from Neanderthals)
http://www.praguepost.com/articles/2007/04/25/dna-unmasks-czech-past.php
(1000 year old Czech DNA)
http://www.msnbc.msn.com/id/21015458/ (Mammoth DNA- techniques for
extracting DNA from ancient hair.)
http://www.foxnews.com/story/0,2933,298316,00.html (very good
Mammoth DNA from hair)
http://deposit.ddb.de/cgi-bin/dokserv?idn=982142943&dok_var=d1&dok_ext=pdf&filename=982142943.pdf
(3000 year old DNA from
the Lichtenstein Cave within the
region of the Jastorf culture, in Lower Saxony)
http://www.genebaze.cz/cgi-bin/res/ydres_LCm.cgi?lang=us&n=cz
(Lichtenstein Y-DNA results)
http://www.sciencedaily.com/releases/2008/04/080403141109.htm
(14,000 year old Native American DNA from Coprolites)
http://www.sciencedaily.com/releases/2008/05/080529141347.htm
http://dna-forums.org/index.php?showtopic=3991&hl= (Cro-Magnon
mtDNA 28,000 years old)
DNA databases:
http://www.ysearch.org/ (Y-Search
Public database run by FTDNA)*****
http://freepages.genealogy.rootsweb.com/~geneticgenealogy/ysid2.htm
(Y-Search-Search Utility, search be ID)*******
http://freepages.genealogy.rootsweb.com/~geneticgenealogy/ytex2.htm
(Y-Search-Search Utility, search by haplotype)*******
http://freepages.genealogy.rootsweb.com/~geneticgenealogy/y.htm
(Y-Search-Search Utility, by Leo Little)
******* http://www.ybase.org/default.asp (Y-Base Public database) ***
http://www.ystr.org/
http://ystr.org (20,000+ database, recently improved
search features.) www.yhrd.org
www.ystr.org (Y-STR
database)
http://freepages.genealogy.rootsweb.com/~geneticgenealogy/yhrd.htm
(Search utility for searching European locations on YHRD) http://www.contexo.info/megaspreadsheet.htm
(Y-STR Allele frequencies)
http://www.ybase.org/statistics.asp
(Y-STR Allele frequencies)
http://ystr.charite.de/index_gr.html
(Haplotype reference database)
http://smgf.org/page.jspx?name=sorensondatabase (SMGF database) ****
http://freepages.genealogy.rootsweb.com/~geneticgenealogy/SMGF/search4.htm
(Search engine for Sorenson database by Leo Little)
http://www.dna-fingerprint.com/modules.php?op=modload&name=ymatch
(Y-Match DNA Fingerprint database)
http://smgf.org:8081/pubgen/site28.jsp
(Sorensen Moelcular Genealogy Foundation- Database- also for an article
about Jim
Sorenson, founder of the database see...
http://www.sacbee.com/content/news/story/10454610p-11374060c.html
) http://new.relativegenetics.com
(Relative Genetics... new database, URL may change after testing)
http://www.oxfordancestors.com/members/yline/?msg=noresults
(Oxford Ancestors Database- may need to log on a guest. From FTDNA
calibration, "You'll need to convert your DYS389 numbers: subtract 3 from both
DYS389-1 and DYS389-2, then subtract DYS389-1 from DYS389-2 to get DYS389ii-i (Roman
numeral two minus one). For example, if your results are 13-29, you would enter 10-16 at
OA. You will also need a value for DYS425 -- 12 is a very strong modal in several
haplogroups, although I don't know about J1. Not many companies measure DYS425.")
http://www.dna-fingerprint.com/user.php?op=register&module=NS-NewUser
(DNA Fingerprint database, new user)
http://www.sun-herald.com/NewsArchive2/061904/tp3np3.htm?date=061904&story=tp3np3.htm
(Adopted child/parent DNA database)
www.identigene.com/SWIMX/Products/dff_main.asp
(Adopted child/parent DNA database)
http://www.familytreedna.com/public/adoptees/ (Adoptees DNA
Project) http://www.donorsiblingregistry.com/ (Donor Sibling Registry)
http://www.africanancestry.com/databasemain.html
(African Ancestry Database)
http://www.mymcgee.com/tools/yutility.html
(Y-DNA comparison utility programme, not a database, but can be used in conjunction
with databases).
http://www.appliedbiosystems.com/yfilerdatabase/
(Y Filer Database)
http://www.mymcgee.com/tools/yutility.html
(McGee DNA comparison utility)*
http://www.dna-fingerprint.com/index.php?module=pagesetter&tid=1&filter=locus:like:385
(DNA fingerprint database)
http://www.ystrlog.org/ (Y-DNA)
http://marylb.free.fr/cgw30/fc30pa10.htm
(Les patronymes étudiés)
http://www.cstl.nist.gov/biotech/strbase/NISTpop.htm
http://afrigeneas.com/forum/index.cgi?noframes;read=45572
(Reference to Howard University African American DNA Datrabase)
http://www.cstl.nist.gov/div831/strbase/str_yh4.htm
(NIST reference page)
http://www.ystr.org/index_gr.html
(Y database)
http://groups.yahoo.com/group/DNA-ANTHROGENEALOGY/database?method=reportRows&tbl=1
(SNP Database), first go to
http://groups.yahoo.com/group/DNA-ANTHROGENEALOGY/
and become member to access database
http://uk.geocities.com/hensoncymru/DNA/DYF399S1-R1bResults.JPG
(DYF399S1 database)
http://www.geocities.com/mcewanjc/s21.htm
(J McEwan's SNP Database)
http://www.journals.uchicago.edu/AJHG/journal/issues/v74n6/41028/datafile1.txt?erFrom=8617029170130421322Guest
(Kayser data on 8 samples from different haplogroups, with many markers
tested... interesting, shows also different STR markers available.)****
http://www.journals.uchicago.edu/AJHG/journal/issues/v74n6/41028/41028.html
(Kayser article relating to above... not a database)
http://www.scottishdna.net/
(Scottish Clans databases)
http://amadeus.biosci.arizona.edu/%7Ekcaldero/str.php (?)
http://www.appliedbiosystems.com/yfilerdatabase/ (Y-Filer
Database) http://www.genebaze.cz/cgi-bin/cyd.cgi?lang=us (Czech Y-DNA
Database) http://www.jpac.pacom.mil/CIL/FRS_Home.htm (Database of mtDNA of
missing USA military persons.)
http://www.jpac.pacom.mil/FRS_public/FRS_public.aspx (Search
missing military persons surnames)
Full
genome sequences:
http://huref.jcvi.org/
(Venter R1b)
http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi
(Venter R1b)
http://jimwatsonsequence.cshl.edu/cgi-perl/gbrowse/jwsequence/
(Watson R1b)
http://yh.genomics.org.cn/mapview.jsp
(Han Chinese- haplogroup O?)
http://yh.genomics.org.cn/
http://www.dna-fingerprint.com/user.php?op=userinfo&uname=HUGO (Hugo
reference sequence Mixed haplogroups, includes mostly R1b, some G, some
I)
ftp://ftp.ncbi.nih.gov/pub/TraceDB/ShortRead/SRA000271/
(in the directory fastq the sequence for the Yoruba NA18507 is
available.)
Craig Venter:
http://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=19621
James Watson:
http://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=28335
Yoruba NA18507:
http://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=29429
http://genome.cshlp.org/content/early/2009/05/26/gr.092197.109
(Korean full sequence)
ftp://ftp.kobic.kr/pub/KOBIC-KoreanGenome/ (Korean full sequence
data)
DNA-Mailing Lists/ DNA Forums/
Blogs etc:
(some useful pointers on posting messages on
mailing lists The news.newusers.questions FAQ
http://www.plig.net/nnq/nquote.html
How to post to uk news groups
http://www.usenet.org.uk/ukpost.html
Proper quoting style explained
http://www.uwasa.fi/~ts/http/quote.html
)
http://lists.rootsweb.com/index/other/DNA/GENEALOGY-DNA.html
(join list/ search archives etc)
http://lists.rootsweb.com/index/other/Miscellaneous/GENEALOGY-DNA.html
(DNA Forum archives)
Search the GENEALOGY-DNA archives
Browse the GENEALOGY-DNA archives
http://lists.rootsweb.com/index/other/DNA/
*** http://www.dna-forums.org/
(DNA
Forum) DNA-NEWBIE-subscribe@yahoogroups.com
("Newbie" DNA discussion list)
http://members.aol.com/dnacousins/Welcome.txt
(DNA list welcome message) http://www.isogg.org/ (International Society Of
Genetic Genealogists- membership is free)***
http://www.ybase.org/forum/forum_topics.asp?FID=518
(Marsh DNA Forum run by DNA Hertiage)
http://members.aol.com/dnacousins/Welcome.txt
(Welcome message to DNA list, gives FAQ about DNA, good intro)**
http://listsearches.rootsweb.com/cgi-bin/listsearch.pl
(enter "Genealogy-DNA" to search DNA list)
http://www.familytreeDNA.com/facts_genes.asp?act=past
(FTDNA monthly DNA magazine- back issues)
http://www.familytreeDNA.com/fgregister.asp
(to subscribe to FTDNA Facts and Genes- DNA monthly magazine)
http://genforum.genealogy.com/dna/
(DNA forum)
http://j.webring.com/hub?ring=dnasurnameprojec&list&page=0
(DNA web ring)
http://www.familytreedna.com/forum/<http://www.familytreedna.com/forum/
(FTDNA Forum.)
http://ttatw.com/mailman/listinfo/truth_ttatw.com
(List to discuss religious or Biblical correlations with DNA-genealogy)
SCOT-DNA-L@rootsweb.com (Scots DNA Mailing list)
http://www.familytreedna.com/forum/forumdisplay.php?s=&forumid=64 (R1b
Forum) http://www.afrigeneas.com/forum-dna/ (African American DNA
Research Forum) http://vandermerwede.org/forums/index.php (van der Merwede Forum)
http://groups.yahoo.com/group/dna-anthrogenealogy/
(Anthrogenealogy)
http://spittoon.23andme.com/
(Blogs including information about "23andme")
http://dnaancestry.typepad.com/blog/ (DNA Ancestry blog)
http://rjgg.molgen.org/index.php/RJGGRE
(Russian journal of genetic genealogy)
DNA sample storage systems: (For those wanting to store DNA from family members for future testing. As DNA
technology improves, it is likely that many more sophisticated tests will be available in
the future. Several manufacturers offer test kits which are believed would store DNA
for 30 years.)
http://www.genetic-identity.com/DNA%20Archving/dnabanking.html
http://www.dnafiler.com/
www.dnagenotek.com. They are a Canadian
company that makes the Oragene saliva collection kit which, when capped, releases
purifying chemicals and allows storage at room temperature for many years.
Video/ Audio on DNA projects/ subjects:
http://www.FamilyTreeDNA.com/videoaudio.html
(Genealogy by genetics video)
http://www.itconversations.com/shows/detail255.html
(Spencer Wells audio lecture on DNA, 51 minutes)
http://www.testsite.co.za/
(National Geographic DNA Project Conference May 2006, Video)
http://www.rootstelevision.com/players/player_dna.php?bctid=316039826
(Various DNA Videos)
http://www.rootstelevision.com/players/player_dna.php?bctid=1351299777
http://www.isogg.org/dnastories.htm
http://www.bradshawfoundation.com/journey/ (Journey of
Mankind)
Genetic books & articles on line/ on line DNA libraries etc:
http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowTOC&rid=mga.TOC&depth=10
(Genetic book)
http://www.familytreedna.com/library.html
(Library of Scientific papers on DNA)
http://www.leicester.ac.uk/genetics/maj4/SurnamesForWeb.pdf
(Surnames and genetics)
http://www.le.ac.uk/genetics/maj4/JoblingTS.03.NRG.Review.pdf
(Good technical article of Y chromosome)
http://vetinarilord.blogspot.com.
www.historicalgeneitcs.com
http://www.jogg.info (Genetic Genealogy Journal-
free- on line) www.familytreedna.com (DNA reference articles
on line....click on "Library" and then "Y-DNA")
http://www.familytreeDNA.com/library.html (FTDNA library of
research articles)
Genetic books not available on line:
http://www.kerchner.com/books/dnabooks.htm (DNA Books)
http://www.amazon.co.uk/exec/obidos/ASIN/1841196975/geogene-21/202-1068448-3891867
(Out of Eden: The Peopling of the World- Openheimer)
http://www.amazon.co.uk/exec/obidos/ASIN/0141008326/geogene-21/202-1068448-3891867
(The Journey of Man: A Genetic Oddesy- Spencer Wells)
http://www.amazon.com/exec/obidos/ASIN/1550025368/
(Trace your roots with DNA- Chris Pomery)
http://honoringourancestors.com/books.html
("Trace Your Roots with DNA" by Smolenyak and Turner)***
http://fairuse.100webcustomers.com/fuj/salon10.htm (Review of
"Before the Dawn" a book on DNA genealogy by Nicholas Wade)
http://www.rootstelevision.com/players/player_dna.html (DNA- genealogy
stories etc) http://astore.amazon.com/genpagecom-20/
www.bloodoftheisles.net
http://www.abrahamschildren.net
http://www.genealogymagazine.com/entine.html
http://www.thegeneticgenealogist.com/wp-content/uploads/InterpretingTheResultsofGeneticGenealogyTests.PDF
(free booklet on genetic genealogy)
http://hpgl.stanford.edu/publications.html (Stanford genetics
publications free on line)
Genetics course:
http://www.edoutreach.washington.edu/openuw/asp/transform.asp?course=Genetics&xml=genetics_intro1
(free on line course)
DNA & Privacy Laws etc:
http://cerbere.ca/genetique/empreintes-génétiques.htm (French law
on genetic testing)
http://www.opsi.gov.uk/acts/acts2004/40030--d.htm#45
(Non-consensual analysis of DNA is at section 45)
http://www.ornl.gov/sci/techresources/Human_Genome/elsi/legislat.shtml
(USA genetics legislation)
http://www.copyright.gov/circs/circ65.html#definition (Issues re
copyright)
http://www.copyright.gov/circs/circ66.html#databases (Issues re
copyright)
http://www.copyright.gov/help/faq/faq-protect.html#website (Issues
re copyright)
http://admi.net/code/CSANPUNL-L1131-1.html (Some French laws)
http://www.aslme.org/dna_04/work3/report.php
http://www.cancerdiagnosis.nci.nih.gov/specimens/50_state_survey/caseStudies3.htm
http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0060073&ct=1
(Research Ethics Recommendations)
Mitochondrial DNA: (Mitochondrial DNA, which descends down the direct female line of ancestors, is unrelated
to Y-DNA used for the Marsh Surname Project. However, some participants may obtain
Mitochondrial DNA tests as part of additional tests offered by the test company.
Mitochondrial DNA is not the focus with this project, but some limited references will be
included here for those who wish to widen there interest to mtDNA.)
http://worldfamilies.net/mtDNA.htm
(General info)
http://www.argusbio.com/tools_docs/world_tree7.3.pdf (mtDNA Tree)
*****
http://www.phylotree.org/
(mtDNA Tree)
******
http://www.mitomap.org/
http://www.geneticorigins.org/geneticorigins/mito/mitoframeset.htm
http://www.mitomap.org/mitoseq.html (Revised Cambridge
Reference Sequence)
https://www2.carolina.com/webapp/wcs/stores/servlet/ProductDisplay?jdeAddressId=&catalogId=10101&storeId=10151&productId=18909&langId=-1&parent_category_rn=&crumbs=n
(mtDNA testing for school projects)
http://www.isogg.org/ancientdna.htm
(Ancient mtDNA)
http://www.jogg.info/32/logan.htm (estimated mtDNA of Eve)
http://www.argusbio.com/sooryakiran/gensnip/gensnip.php (Programme to
analyze mtDNA)
http://ghr.nlm.nih.gov/ghr/template/gen,chromosome,MT.vm (Genetics
home reference page)
www.ilbg18230.pwp.blueyonder.co.uk/programs/analyser.htm (mtDNA mutation
lists) http://www.familytreednacom/mtDNA_tutorial.html>
(mtDNA tutorial)http://www.isogg.org/famousdna.htm
(mtDNA of famous people)
http://www.isogg.org/neanderthaldna.htm (Neanderthal mtDNA)
http://scs.uiuc.edu/~mcdonald/worldmtdnamap.pdf
(World map with mtDNA haplotypes distribution)
http://www.bioanth.cam.ac.uk/mtDNA/
(Mitochondrial DNA Concordance)
http://www.mitosearch.org/ (FTDNA
Mitochondrial Database)
http://www.genpat.uu.se/mtDB/index.html
(mtDNA Database)
http://www.genpat.uu.se/mtDB/
(mtDNA database where you can query one base at a time)
http://www.fbi.gov/hq/lab/fsc/backissu/april2002/miller1.htm#Accessing%20the%20mtDNA%20Population%20Database
(mtDNA Database)
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=nuccore
(Some full mtDNA sequences- type "family Tree DNA" into search box)
http://home.earthlink.net/~wilsondna/FILE_DOWNLOAD_PAGE.htm
(mtDNA Database- based on mitosearch)
http://www.nature.com/nature/journal/v404/n6777/fig_tab/404490a0_F2.html
(Neandethal mitochondrial DNA- see also DNA forum posting 2 Dec 2004)
http://freepages.genealogy.rootsweb.com/~ncscotts/mtDNA/Neanderthal%20mtDNA.pdf
(Neanderthal mtDNA sequences)
http://freepages.genealogy.rootsweb.com/~jswdna/jchart.gif (J
Haplogroup)
http://tech.groups.yahoo.com/group/J-mtDNA/ (J Haplogroup)
http://www.familytreedna.com/(iwlk1yuk04p51t2firjs1445)/public/J1b1/index.aspx
(J Haplogroup DNA Project)
http://worldfamilies.net/mtdna/jstar/index.html (J* haplogroup
project)
http://tech.groups.yahoo.com/group/J-mtDNA/ (J haplogroup
discussion group) http://www.familytreeDNA.com/hclade.html
(mtDNA Haplogroup H)
http://freepages.genealogy.rootsweb.com/~wrhurst/mtdna-k/k500post.htm
(Haplogroup K survey)
www.gen.tcd.ie/molpopgen/data.html
(Irish mtDNA database)
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16151183&query_hl=1
(Brittish mtDNA)
http://www.mcdonald.cam.ac.uk/genetics/labpubs.html#anchor1565740
(Includes showing mtDNA haplotypes spreading out of Africa)
http://www.tracegenetics.com/services_research_library.html
(Library of mtDNA studies)
http://news.yahoo.com/news?tmpl=story&u=/afp/20040527/sc_afp/sweden_science_health_genetics_aging_040527140653
(mtDNA & the aging process)
http://www.newscientist.com/hottopics/dna/article.jsp?id=23974800&sub=Ancestry
(Viking mtDNA) http://www.mtdnalog.org/ (mtDNA test log)
http://www.guardian.co.uk/italy/story/0,12576,1256459,00.html
(Medici family)
http://bioweb.usc.edu/documents/bisc406-lab_luke.pdf
(DNA of the body attributed to the Evangelist Luke?) # Marie Antoinette is haplogroup H, HVR1 T16519C, HVR2 T152C, C194T, A263G and
N315.1C http://www.pnas.org/cgi/content/full/98/2/537
(Ancient mtDNA Australia)
http://www.brookingsociety.org.uk/mtdna.htm
(mtDNA analysis programme)
http://www.genetests.org/query?dz=mt-overview (Mitochondrial
disorders)
http://www.ftdna.com/facts_genes.asp?act=show&nk=3.2
(mtDNA mutation rates)
http://archiver.rootsweb.com/th/read/GENEALOGY-DNA/2004-03/1079482461
("Famous" mtDNA haplotypes)
http://www.bionet.nsc.ru/bgrs/thesis/99/
(mtDNA from Pazaryk Caucasian mummies of 2,500 years ago in China)
http://www.tymri.ut.ee/PhD/2004/tambets_thesis.pdf
(Thesis- "THE UNDERSTANDING OF POST GLACIAL SPREAD OF HUMAN MITOCHONDRIAL DNA
HAPLOGROUPS IN EUROPE AND BEYOND: A PHYLOGENETIC APPROACH")
http://www.ilbg18230.pwp.blueyonder.co.uk/mtdna.htm
http://freepages.genealogy.rootsweb.com/~wgeorge/dna/mtdna_cornwall.html
(Cornish mtDNA)
http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=61743586
(NCBI nucleotide site mtDNA Complete Sequences)
http://www.genpat.uu.se/mtDB/
(University of Uppsala, a search engine to look for particular mutations)
www.brookingsociety.org.uk/mtdna.htm
(phylogenetic trees for most of the sequences)
http://www.geneticancestor.com/ (mtDNA
in Europe, research project)
http://www.bloodoftheisles.net/OGAP_mDNA.pdf (Sykes mtDNA
sequences) http://www.genpat.uu.se/mtDB/
(2000+ mtDNA sequences)
http://freepages.genealogy.rootsweb.com/~ncscotts/mtDNA/mtDNA%20HVR1%20Mutation%20Distribution.htm
(8,000+ mtDNA sequences)
http://www.ianlogan.co.uk/ (mtDNA-
interesting site)
http://www.ianlogan.co.uk/haplogroup/instructs.htm (List of full
mtDNA sequences)
http://genetics.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pgen.0030104#toclink3
(Nat Geo mtDNA Database)
http://www.genebase.com/blog/
(Blogs on mtDNA)
https://www3.nationalgeographic.com/genographic/resources.html
http://www.mitomap.org/cgi-bin/tbl6gen.pl (mtDNA mutations- list)
X-Chromosome
DNA:
http://davidkfaux.org/X_CHROMOSOME_Haploblock_Resources.pdf
(X-Chromosome resources)
http://davidkfaux.org/X_Facts.pdf
7) MUTATION RATES FOR INDIVIDUAL Y-DNA MARKERS
http://www.worldfamilies.net/marker.htm (collection of STR mutation rate
estimates) http://www.jogg.info/22/Chandler.htm (John Chandler mutation rate
estimates)
Mutation rates as on DNA List
Posting 16 June 2008:
I don't recall that anyone on the list has ever tried to define the
breakpoints between slow, medium, and fast mutating markers before. As
others have mentioned, this is an arbitrary decision. I sorted the 67
markers in the FTDNA 67 marker panel as well as 9 markers included in
the SMGF 43 marker panel that aren't included in the FTDNA 67 marker
panel by their mutation rates as found on Leo Little's web site at
http://freepages.genealogy.rootsweb.ancestry.com/~geneticgenealogy/ratestuff
.htm. The mutation rates were calculated by John Chandler. These
rates are probably among the most accurate mutation rates that have been
published to date. I arbitrarily chose a mutation rate of 0.001 as the
breakpoint between slow and medium mutating markers. I arbitrarily chose
a mutation rate of 0.005 as the breakpoint between medium and fast
mutating markers. I hope you find this list of help to you. Feel free to
chose different breakpoints if you prefer.
Sincerely,
Tim Janzen
Marker Type Rate Testing Company
472 slow 0.00001 FTDNA
578 slow 0.00008 FTDNA
426 slow 0.00009 FTDNA, SMGF
454 slow 0.00016 FTDNA, SMGF
455 slow 0.00016 FTDNA, SMGF
425 slow 0.00018 FTDNA
436 slow 0.00018 FTDNA
641 slow 0.00018 FTDNA
490 slow 0.00019 FTDNA
450 slow 0.0002 FTDNA
388 slow 0.00022 FTDNA, SMGF
594 slow 0.00029 FTDNA
395s1 slow 0.00031 FTDNA
395s1 slow 0.00031 FTDNA
640 slow 0.00034 FTDNA
531 slow 0.00037 FTDNA
492 slow 0.00042 FTDNA
617 slow 0.00042 FTDNA
392 slow 0.00052 FTDNA, SMGF
568 slow 0.00053 FTDNA
462 slow 0.00053 SMGF
590 slow 0.00054 FTDNA
438 slow 0.00055 FTDNA, SMGF
537 slow 0.00057 FTDNA
393 slow 0.00076 FTDNA, SMGF
565 slow 0.00087 FTDNA
B07 slow 0.00093 SMGF
487 slow 0.00097 FTDNA
437 slow 0.00099 FTDNA, SMGF
YCAIIa medium 0.00123 FTDNA, SMGF
YCAIIb medium 0.00123 FTDNA, SMGF
511 medium 0.00128 FTDNA
459a medium 0.00132 FTDNA, SMGF
459b medium 0.00132 FTDNA, SMGF
441 medium 0.00132 SMGF
448 medium 0.00135 FTDNA, SMGF
19 medium 0.00151 FTDNA, SMGF
406s1 medium 0.00154 FTDNA
463 medium 0.00162 SMGF
389i medium 0.00186 FTDNA, SMGF
413a medium 0.00202 FTDNA
413b medium 0.00202 FTDNA
H4 medium 0.00208 FTDNA, SMGF
572 medium 0.00212 FTDNA
385a medium 0.00226 FTDNA, SMGF
385b medium 0.00226 FTDNA, SMGF
461 medium 0.00233 SMGF
C4 medium 0.00236 SMGF
389ii medium 0.00242 FTDNA, SMGF
520 medium 0.00245 FTDNA
447 medium 0.00264 FTDNA, SMGF
391 medium 0.00265 FTDNA, SMGF
445 medium 0.00296 SMGF
390 medium 0.00311 FTDNA, SMGF
452 medium 0.00314 SMGF
557 medium 0.00321 FTDNA
444 medium 0.00321 FTDNA, SMGF
442 medium 0.00324 FTDNA, SMGF
446 medium 0.00365 FTDNA, SMGF
A10 medium 0.00379 SMGF
460 medium 0.00402 FTDNA, SMGF
607 medium 0.00411 FTDNA
439 medium 0.00477 FTDNA, SMGF
481 fast 0.00544 FTDNA
464a fast 0.00566 FTDNA, SMGF
464b fast 0.00566 FTDNA, SMGF
464c fast 0.00566 FTDNA, SMGF
464d fast 0.00566 FTDNA, SMGF
456 fast 0.00735 FTDNA, SMGF
570 fast 0.0079 FTDNA
458 fast 0.00814 FTDNA, SMGF
534 fast 0.00832 FTDNA
449 fast 0.00838 FTDNA, SMGF
576 fast 0.01022 FTDNA
CDYa fast 0.03531 FTDNA
CDYb fast 0.03531 FTDNA
Mutation rates is a technical issue which participants in the Marsh DNA Project
don't really need to know about: I don't intend to leave this section on mutation
rates permanently here. It is only here until I get well enough
organized to put it
somewhere else (ie it might end up being here permanently). The importance of
mutation rates, is that to get a feel for how long ago two people may have had a common
ancestor, you need to know what mutation rates are, to apply statistical formulas.
Because DNA science is relatively new, and mutations are relatively rare, there is still
not enough statistical data for experts to agree on mutation rates. Some studies say
average mutation rates are 0.0015, and other studies say it may be 0.0042.
By some accounts, the mutation rate of 0.0029 is the for the average for the first
25 FTDNA markers. However, some claim the FTDNA figures are too high,
and the rate is closer to 0.002. (The average will vary depending on which set of markers you are
considering, eg, 12, 25, 37 etc. The first 12 markers of FTDNA tend to be slower
mutating than the other markers.) An important research study by FTDNA on
mutation
rates is due to be published in the first half of 2004.
On the Genealogy-DNA list (Doug MacDonald, 29 Feb 2004, and 2? Mar 2004), one
contributor produced his estimates of individual marker mutation rates based on the
Sorensen Molecular Genealogy database. He stresses these are only his analysis, but
the results look interesting (Following copied from the DNA List)...
Here is a second look at the Sorenson rates. None have changed from my first list by a significant amount. The slowest ones dropped a bit, and in fact they may actually be as low as .0004. They are hard to back-calculate.
Again, this is Sorenson's data, not mine. I merely reverse engineer assuming Walsh's infinite alleles model. I have done several different methods of checking and all agree. The error bars are of course known only to Sorenson. Hopefully they will publish soon.
Marker Rates 385 .0033 (*) 388 .0005 389I .0021 389II .0028 390 .0045 391 .0036 392 .0016 393 .0012 19 .0016 426 .0005 437 .0020 438 .0012 439 .0045 447 .0045 448 .0028 449 .0075 454 .0005 455 .0005 458 .0066 459 .0014 (*) 460 .0028 461 .0028 462 .0005 ggaat1b07 .0013 ycaii
.0014 (*) ygataa10 .0045 ygatac4 .0028 ygatah4 .0036
Note: the values marked by a (*) have been divided by two from what Sorenson uses.
This is because they are double markers. What Sorenson is doing is counting the pair as one marker. If either changes they count this as one mutation. If you do this, you need to double the rate I show here. If you count the marker twice, as two markers, the best you can do is use the rates I show here, which are half what Sorenson uses. They could, of course, actually be two different rates which average the value I give in this list. The two 389 values are listed separately and does not suffer this ambiguity.
The average for the FTDNA 12 set is .0025. You cannot calculate it for the other FTDNA sets because this set lacks 464. Assuming 464 is fast, it would be about .0028 to .0030.
You can calculate the averages yourself for other sets (except of course ones that Sorenson does not use.)
There is a factor of (about) 15 in rate from the slowest to the fastest. Why?
Following is an alternative estimate by Doug MacDonald on the
DNA Forum 28 Nov 2004, based on different sources.
393 0.0014 390 0.006 19 0.0025 391 0.0059 385a 0.005 385b 0.005 426 0.0007 388 0.0018 439 0.008 389-1 0.0035 392 0.002 389-2 0.0052 458 0.0095 459a 0.0025 459b 0.0025 455 0.0007 454 0.0007 447 0.0075 437 0.0027 448 0.004 449 0.015 464a 0.0063 464b 0.0063 464c 0.0063 464d 0.0063 460 0.0065 gatah4 0.0075 ycaiia 0.004 ycaiib 0.004 456 0.01 607 0.0095 576 0.015 570 0.014 cdya 0.017 cdyb 0.017 442 0.006 438 0.002
Mutation rate study by Charles Kerchner- as at March 2008:
All:
Since my last update I have received some more 37 and 67 marker
haplotype data entries.
Here are the latest average YSTR mutation rates for the various YSTR
panel sizes which have been entered by Surname Project Admins into my
"Y-STR Haplotype Observed Mutation Rate Log" and YSTR mutation rate
study. These rates are for the four FamilyTreeDNA marker panels,
including the newest 30 marker 30(38-67) upgrade panel to 67 markers. I
also show the composite YDNA37 37 marker and
YDNA67 67 marker haplotype rates. These averages are computed from
thousands of marker mutation opportunities (MMOs). See the project for
more details on that.
More 67 marker haplotype project entries and updates to prior entries
are encouraged. If you already have an older entry you made years or
months ago into my YSTR Mutation Rate Log for your project, consider
updating it with any newer data you have accumulated, including the
newer 67 marker testing. The data below is from 50 surname projects
tested to 37 markers or 67 markers as of the 13 Mar
2008 data date.
YSTR Panels and Haplotypes
Observed Weighted Average Mutation Rates and MMOs
-------------------------------------------------
12(1-12) panel 0.0025 +- 0.0003 (26,568)
13(13-25) panel 0.0031 +- 0.0003 (28,301)
12(26-37) panel 0.0071 +- 0.0005 (25,164)
30(38-67) panel 0.0017 +- 0.0004 ( 8,640)
12(1-12) haplo 0.0025 +- 0.0003 (26,568)
25(1-25) haplo 0.0028 +- 0.0002 (54,425)
37(1-37) haplo 0.0042 +- 0.0002 (81,992)
67(1-67) haplo 0.0031 +- 0.0004 (19,296)
For more details about these panel's average mutation rates and other
panels and haplotype sizes mutation rates, see the summary PDF data
table file link in the YSTR Mutation Rate Log website. These rates are
possibly useful to other scientists or hobby scientists as
calibration/reference points for other methodologies in studying average
YSTR mutation rates and/or individual marker mutation rates. I am
collecting the data to further knowledge in this new field and to be
helpful to all. I ask for your cooperation and understanding and help
with gathering more participants and thus data:
http://www.ystrlog.org/
Also, take a look at the 37 marker histogram page which shows some
interesting observed differences if average mutation rates observed from
one haplogroup to another. Particularly take a look at the difference
between R1b, I1a, and R1a histograms. Limited data yes, but some
interesting early signals, imo.
http://www.kerchner.com/ystrlog/ystr1to37histogram.htm
As the robot in short circuit said ... "more data". I need more data.
Project Admins are encouraged to submit more entries for "known to be
related" tested males who share a known Most Recent Common Ancestor (MRCA)
for a related group or cluster in your surname project. Your shared data
contributes to the knowledge base for this new field. See the project
website for more details about the project, who can join, and how to
submit data. It is not all that hard to do and of course I am willing to
help you. But you need to know the traditional paper trail genealogy
from the MRCA for the group/cluster being submitted. The add entry form
has now been automated to do all the arithmetic calculations of the
mutation rates.
My project also has been documenting some very old family tree
pedigrees proven by both traditional genealogy research and YDNA
testing. See the project website for more details on that. See my long
standing challenge at the top of the log page. Do you have an old proven
pedigree to share, proven by both paper trail and YDNA testing? If so,
please consider submitting it to my log.
http://www.ystrlog.org/
My project is now over three years old. I need more data. Please
spread the word about this project and encourage people who have
relevant data to join. Sharing your data is helpful to all.
Synergy at Work!
Charles Kerchner
(P.E. Retired)
Emmaus PA USA
Project Admin
Kerchner's YSTR Mutation Rate Log and Study:
http://www.ystrlog.org/
http://www.kerchner.com/dna-info.htm
NEW DNA MUTATION RATE STUDY RELEASED NOV 2004:
FTDNA released results of a study Nov 2004. The way data was collected, it has been
questioned by some if it may have biased results. However, in the absence of good
information, it is a significant study. This indicates the mutation rate is faster
than originally thought. The average mutation rate of the markers used by FTDNA is as
follows....
Markers 1-12 = 0.0040 Markers 13-25 = 0.0048 Markers 26-37 = 0.0075 Markers 1-25 = 0.0044 Markers 1-37 = 0.0054
(Doug MacDonald said some indications from other sources are 1-12 =
0.0022, 1-25 = 0.0027, 1-37 = 0.0036)
In simple terms, this means that on average, you might expect one mutation every 21
generations with 12 markers, every 9 generations with 25 markers, and every 5 generations
with 37 markers.
However, there are a number of factors at play which need to be allowed for. Some
markers, if they have very high or low scores might be more likely to mutate, meaning that
some families might be prone to more mutations than other families. It might also be
significant to take into consideration if it is slow or fast mutating markers which have
mutated. Other markers seem to mutate in more than one step at a time, and this
needs to be considered.
MUTATION RATE STUDIES- FATHER SON PAIRS:
http://archiver.rootsweb.com/th/read/GENEALOGY-DNA/2005-04/1113356244
http://www.springerlink.com/content/e851161060443056/
http://www.springerlink.com/content/47570430mm5m106v/
http://www.yhrd.org/Research/Loci
POSTED ON DNA FORUM 8 MAY 2006: Mutation rates of new FTDNA Markers
most of the new markers were in the supplementary data to the Kayser
paper.
A quick look at the data suggests the following
DYS472 8 or 9, slow. DYS511 10 or 11, slow. DYS531 11-13, slow to medium DYS537 10 or 11, slow DYS594 8-11, slow DYS578 7-10, slow DYS590 8-9, slow DYS641 7-10, slow DYF395S1/2 13-14, medium (but with possible recombination mutations) DYF406S1 10-14, medium DYS436 8-12, slow DYS444 9-17, medium/fast (see SGMF stats) DYS446 8-23, medium/fast (see SGMF stats and Whit's recent paper). DYS481 22-27, fast (very?) DYS490 12-14, slow/medium DYS520 18-24, fast? (appears to contain 2 variable repeat sections) DYS534 14-16, medium DYS557 14-23, medium/fast DYS492 11-13, slow DYS565 10-12, slow DYS572 10-11, slow
ISOGG Article:
Mutation rate Article in ISOGG by John Chandler
http://www.jogg.info/22/Chandler.htm
8) COMPARISONS OF MARKER NAMES BEWTEEN LABS:
Some DNA labs have slightly different marker names, and calibrations. To compare
markers between labs, some adjusments need to be made. As at 3 March 2004, following
is comparative list, but this is likely to soon be changed, as labs reach agreement on
standard systems. (Another description on camparing results from different labs can
be found at http://www.kerchner.com/labmerge.htm)
See also http://smgf.org:8081/pubgen/site40.jsp
***.
Although not shown below, I beleive GATTA H4 has some variation between the labs.
For example, there is a difference of 1 between FTDNA and Sorenson.
Locus DYS# FTDNA/ REL GEN/ HERITAGE/ SORENSEN
1 393 1 393 1 393 1 393 2 390 2 390 2 390 2 390 3 19*/394 3 394 3 394 3 394
+1 (FT RG)
4 391 4 391 4 391 4 391 5 385a 5 385a 5 385a 5 385a 6 385b 6 385b 6 385b 6 385b 7 426 7 426 7 426 7 426 8 388 8 388 8 388 8 388 9 439 (A4) 9 439 9 439 9 439 10 389-1 10 389-1 10 389-1 10 389-1 11 392 11 392 11 392 11 392 12 389-2 12 389-2 12 389-2 12 389-2 13 458 13 458
14 459a 14 459a 15 459b 15 459b 16 455 13 455 16 455 17 454 14 454 17 454 18 447 15 447 18 447 19 437 16 437 13 437 19 437 20 448 20 448
+3 (FT RG)
21 449 21 449 22 464a - 23 464b -
24 464c - 25 464d - 26 460 17 460 14 460 22 460 27 GATA H4 18 H4 15 H4 23 H4 28 YCA II a 19 YCAIIa 24 YCA11a 29 YCA II b 20 YCAIIb 25 YCA11b 30 456 -
31 607 - 32 576 - 33 570 - 34 CDY a - 35 CDY b - 36 442 -
37 438 21 438 16 438 26 438 22 461 17 461 27 461 23 462 18 462 28 462 24 BO7 29 B07 25 A10 19 A10 30 A10 26 C4 20 C4 31 C4 21 425 -
Nomenclature changes June 2004:
http://www.ybase.org/convert.asp
DNA Forum posting 29 Sept 2005 by John Chandler....
Time for another update on mutation rates. I downloaded 2122 37-marker haplotypes from Ysearch, representing a mix of haplogroups, and used the method described in the SMGF poster ASHG 2004-4, entitled "Direct determination of mutation characteristics of Y chromosome STR loci," to determine the mutation rates. However, I used the recently augmented YHRD table of direct mutation-rate measurements from father-son pairs as the calibration. I also converted the reported SMGF rates to the same new calibration scale for comparison. Finally, I computed the average rates for a variety of panels and tossed in the corresponding panel averages announced by FTDNA at last year's conference and the ones calculated from Charles Kerchner's log as of now. Note: the multi-copy markers are shown here with the rate for each copy assuming equipartition, and the panel averages are computed by counting each copy as a separate marker.
Note the peculiarity of the log data: the average for 1-25 is higher than either 1-12 or 13-25. This suggests a bias in the decisions to upgrade from 12 to 25 -- those with observed mutations in a 12-marker test were significantly more likely to upgrade than those with a 12/12 match. In particular, the average rate for the 12-marker tests of those who upgraded is 0.00267, while the average for those who did not upgrade is 0.00175. This effect would be even stronger if we could count the 11/12 near-matches that exploded upon upgrade and were therefore eliminated from the statistics.
John Chandler
---------------------------------------------------------------------- (This table is formatted to line up more-or-less correctly with
both proportional and fixed fonts.)
Locus ____ --SMGF_ASHG_2004-4--- ____ YSEARCH ____ FTDNA ____ K_Log _____ ____ (poster) ____ (scale) ____ (scale)
385ab ____ 0.002800 ____ 0.00230 ____ 0.00217 388 ______ 0.000379 ____ 0.00031 ____ 0.00040 389i _____ 0.002184 ____ 0.00179 ____ 0.00179 389ii-i __ 0.002584 ____ 0.00212 ____ 0.00219 390 ______ 0.004405 ____ 0.00361 ____ 0.00370 391 ______ 0.003155 ____ 0.00259 ____ 0.00255 392 ______ 0.001488 ____ 0.00122 ____ 0.00136 393 ______ 0.001119 ____ 0.00092 ____ 0.00090 394 ______ 0.001548 ____ 0.00127 ____ 0.00123 426 ______ 0.000271 ____ 0.00022 ____ 0.00024 437 ______ 0.001755 ____ 0.00144 ____ 0.00144 438 ______ 0.001018 ____ 0.00084 ____ 0.00077 439 ______ 0.004181 ____ 0.00343 ____ 0.00349 441 ______ 0.001323 ____ 0.00109 ____ ------- 442 ______ 0.003066 ____ 0.00252 ____ 0.00232 444 ______ 0.002956 ____ 0.00243 ____ ------- 445 ______ 0.000952 ____ 0.00078 ____ ------- 446 ______ 0.003143 ____ 0.00258 ____ ------- 447 ______ 0.003891 ____ 0.00319 ____ 0.00308 448 ______ 0.002375 ____ 0.00195 ____ 0.00202 449 ______ 0.006464 ____ 0.00531 ____ 0.00574 452 ______ 0.001743 ____ 0.00143 ____ ------- 454 ______ 0.000235 ____ 0.00019 ____ 0.00024 455 ______ 0.000312 ____ 0.00026 ____ 0.00032 456 ______ 0.005342 ____ 0.00439 ____ 0.00470 458 ______ 0.005804 ____ 0.00476 ____ 0.00484 459ab ____ 0.001176 ____ 0.00097 ____ 0.00091 460 ______ 0.002942 ____ 0.00241 ____ 0.00241 461 ______ 0.002327 ____ 0.00191 ____ ------- 462 ______ 0.000532 ____ 0.00044 ____ ------- 463 ______ 0.001623 ____ 0.00133 ____ ------- 464abcd __ ------ * ____ ---- ** ____ 0.00279 570 ______ -------- ____ ------- ____ 0.00447 576 ______ -------- ____ ------- ____ 0.00549 607 ______ -------- ____ ------- ____ 0.00309 A10 ______ 0.003794 ____ 0.00311 ____ ------- C4 _______ 0.002355 ____ 0.00193 ____ ------- H4 _______ 0.003044 ____ 0.00250 ____ 0.00259 YCAIIab __ 0.001249 ____ 0.00102 ____ 0.00108 1B07 _____ 0.000925 ____ 0.00076 ____ ------- CDYab ____ -------- ____ ------- ____ 0.00672
Panels: FT1-12 ___ 0.002242 ____ 0.00184 ____ 0.00185 ____ 0.00399 ___ 0.00245 FT13-25 __ 0.002860 ____ 0.00235 ____ 0.00236 ____ 0.00481 ___ 0.00256 FT1-25 ___ 0.002560 ____ 0.00210 ____ 0.00211 ____ 0.00441 ___ 0.00261 FT1-37 ___ -------- ____ ------- ____ 0.00255 ____ 0.00541 ___ 0.00450 RG26 _____ 0.002020 ____ 0.00166 ____ ------- RG43 _____ 0.002410 ____ 0.00198 ____ ------- Norway10__ 0.002245 ____ 0.00184 ____ 0.00185 *** YHRD10 ___ 0.002530 ____ 0.00208 ____ 0.00208 ****
* Used 0.00350 for calculating panel averages. ** Used 0.00287 for calculating panel averages. *** Panel of ten markers used in Norwegian father-son study, with a measured average rate of 0.0020. (Dupuy et al. 2004). **** Panel of ten markers with collected published (or almost published) results, including the Norwegion study, but not the same ten markers.
FOLLOWING MARKERS NOW OFFERED BY ETHNOANCESTRY: (Examples
of typical haplotypes in various haplogroups, and diversity in markers.)
http://www.journals.uchicago.edu/AJHG/journal/issues/v74n6/41028/datafile1.txt
Allele Length of Eight Human DNA Samples Locus
Belonging to Eight Different Y-SNP Haplogroups ID Diversity A
B C E I
J K R DYF406S1 0.87 1* 4*
4* 3* 5* 5* DYS481 0.86 1* 6*
5* 4* 4* 2* 1* 1* DYS487 0.61 14 13
13 14 12 13 13 13 DYS490 0.60
16 14
12 12 12 12 DYS494 0.68 1* 1*
4* 1* 2* 2* 1* 2* DYS505 0.79 13 11
12 13 12 13 10 12 DYS522 0.82 9
13 11 13 12 11 12
11 DYS531 0.71 12 13
11 11 12 12 12 13 DYS533 0.75 10
9 12 12 11 11
11 11 DYS549 0.79 13 10
12 13 12 12 13 14 DYS556 0.81 8
11 12 12 10
11 11 DYS575 0.64 9
12 10 8 10 10
10 10 DYS578 0.82 7
8 9 8 8
7 10 9 DYS589 0.82 2* 4*
1* 1* 3* 1* 2* 3* DYS594 0.46 11
8 11 11 11 10
11 11 DYS636 0.64 9
12 10 10 10 10 10
11 DYS638 0.71 11 12
10 12 10 11 11 11 DYS641 0.64 9
10 10 11 10 10
7 10
MUTATION RATES: Following is a posting to the DNA
List dated 14 Feb 2006 by Doug McDonald:
I have numerous "sets" of numbers. One is just the numbers from the
Sorenson paper, normalized to my own average of the YHRD numbers and the
Kerchner numbers, all properly weighted by number of instances, for the
first FTDNA 12. The second is my own numbers, identically weighted, taken
from data from Ysearch, using a properly weighted, for all Europe, set of
data from R1b, R1a, I, and E3b. The third is just the average of those two
sets, where they overlap.
For the 37 FTDNA numbers these values are (FTDNA order):
Sorenson Mine Average
0.000951331 0.000859077 0.000905204 0.003737371 0.002789068 0.003263219 0.001316574 0.001589313 0.001452943 0.002684112 0.003255742 0.002969927 0.002378327 0.001215556 0.001796941 0.002378327 0.003242745 0.002810536 0.000229339 0.000281880 0.00025561 0.000322773 0.000428446 0.00037561 0.003550502 0.004940802 0.004245652 0.001851697 0.002246961 0.002049329 0.001265610 0.000981038 0.001123324 0.002191458 0.002631745 0.002411602 0.004929932 0.005647866 0.005288899 0.001002295 0.000689137 0.000845716 0.001002295 0.001799793 0.001401044 0.000265014 0.000287363 0.000276189 0.000199610 8.66819E-05 0.000143146 0.003305025 0.003226596 0.003265811 0.001490701 0.001404251 0.001447476 0.002017331 0.001781656 0.001899493 0.005490537 0.006559247 0.006024892 0.003351974 0.001770982 0.002561478 0.003351974 0.002595981 0.002973977 0.003351974 0.004238435 0.003795204 0.003351974 0.003653918 0.003502946 0.002497243 0.003594258 0.003045751 0.002585581 0.003334444 0.002960012 0.001060904 0.000457712 0.000759308 0.001060904 0.002310783 0.001685843 0.004613954 0.005923067 0.00526851 0.007209039 0.003959481 0.00558426 0.007668214 0.007930994 0.007799604 0.006198855 0.006023698 0.006111277 0.011020000 0.009147722 0.010083861 0.011020188 0.009531934 0.010276061 0.002604268 0.003428091 0.00301618 0.000864692 0.000853537 0.000859114
where all those extraneous decimal places are due to the normalization.
I would suggest that one consider the Sorenson rates currently the "best"
and the difference between theirs and mine as an example of the "typical
expected error".
Note the big difference in mine and Sorenson's for the multiple markers like
464 and YCAII. This is because mine actually take into account the
difference in mutation between the higher and lower allele values as
actually found in Ysearch for the different a, b, c, d, etc.
Doug
Posting to DNA Forum re mutation rates of new
markers 29 May 2006
I have calculated rates of the new markers in the Butler paper, using the
SMGF "slope" method. They are normalized to a combination of all father-son
and genealogical line marker rates. For this normalization the FTDNA 12
normalizes to 0.002. I used only the "caucasian" data from Butler. This is a
painful process because the data is in pdf form and has to be printed out
and laboriously scanned back in.
Here they are:
DYS444 0.00224 DYS446 0.00319 DYS449 0.00563 DYS463 0.00204 DYS485 0.00241 DYS495 0.00131 DYS505 0.00408 DYS508 0.00136 DYS520 0.00216 DYS522 0.00451 DYS532 0.00531 DYS533 0.00329 DYS534 0.00548 DYS540 0.00192 DYS556 0.00082 DYS557 0.00358 DYS570 0.00478 DYS576 0.00552 DYS594 0.00074 DYS635 0.00276 DYS643 0.00157
The average of these is in the .0027 range.
Doug McDonald
DNA List posting 8/09/06: Estimate is the average mutation rate of markers 1-37, is 2.3 x faster than
the 38-67 markers.
http://www3.interscience.wiley.com/cgi-bin/abstract/112101932/ (Mutation
rate study)
Mutation rate related to allele length:
http://www.vizachero.com/images/AlleleComp.pdf
Forum Posting:
http://www.familytreedna.com/forum/showthread.php?t=3776
DYS413a - 0.0074 DYS413b - 0.0074 DYS434 - 0.0005 DYS435 - 0.0013 DYS436 - 0.0017 DYS441 - 0.0025 DYS444 - 0.0036 DYS445 - 0.0023 DYS446 - 0.0036 DYS452 - 0.0027 DYS461 - 0.0038 DYS462 - 0.0017 DYS463 - 0.0105 DYS485 - 0.0039 DYS495 - 0.0034 DYS635 - 0.0055 DYS643 - 0.0029 DYS714 - 0.0084 DYS716 - 0.0048 DYS717 - 0.0052 DYS726 - 0.0018 Y-GGAAT-1B07 - 0.001 Y-GATA-A10 - 0.0043
Mutation rates:
http://en.wikipedia.org/wiki/List_of_DYS_markers#Mutation_rates
Mutation rates observed in Charles Kerchner
survey- DNA forum posting 27 Sept 07:
Observed YSTR Haplotype Mutation Rates in Surname Projects Recap:
FTDNA YSTR Panel or ----- ----- Observed
Haplotype Size ----- ----- Mutation Rate
12(1-12) panel ----- ----- 0.0025
13(13-25) panel ----- ----- 0.0029
12(26-37) panel ----- ----- 0.0066
30(38-67) panel ----- ----- 0.0022
12(1-12) YDNA12 ----- ----- 0.0025
25(1-25) YDNA25 ----- ----- 0.0027
37(1-37) YDNA37 ----- ----- 0.0041
(Average for
67 markers about 0.0032)
9) TIME TO MOST RECENT COMMON ANCESTOR (TMRCA):
This is a subject which causes blood pressure to rise amongst some "experts" on
DNA. Different authorities give various statistical projections about how far back
it likely is to a common ancestor for two persons with a particular match or near match in
DNA. These estimates often give a "most likely" TMRCA, however, if you
read the fine print, they all give a huge range of "other possibilities"
if you consider probabilites possible within a 5% to 95% confidence range. Further,
the various authorities base their estimates on assumed data, which often varies between
"experts", and generally widely differing mutation rates are averaged, not
taking into consideration mutation rates of individual markers which mutate.
The problem is, that persons who don't understand the concept of statistical probabilites
well, tend to miss use the data, and make inappropriate conclusions. TMRCA estimates
can be helpful, but they have to be taken into consideration in conjunction with other
evidence.
Following is an exert from a DNA Forum posting 1 May 04 by Richard Cottrell which he has
based on an average mutation rate of 0.002. The "average" muttion rate
will vary depending on the individual markers in the set being considered. Some test
companies have faster mutating markers in their sets of markers which they offer than
offered other test companies. There are different views on what the average mutation
rate is, FTDNA using faster rates in their TMRCA calculators than some other companies,
but they have not released their research data to support these faster rates. There
seems a lot of support for 0.002 the avarage mutation rate for commonly tested markers.
TMRCA estimates...
These are all based on u=.002 ! Please remember it is just an estimation !
48/48 match will yield 50% within 3.6 generations and 95% within 16.07 generations
47/48 match will yield 50% within 8.8 generations and 95% within 25 generations
46/48 match will yield within 50% 14.2 generations and 95% within 33 generations
In comparison with the 37 and 43 marker MRCA:
37/37 match will yield 50% within 4.7 generations and 95% within 20.0 generations
43/43 match will yield 50% within 4.0 generations and 95% within 17.9 generations
DNA Forum
Posting 19 Dec 2008 with estimates of mutation rates of markers:
Marker Type Rate Testing Company
472 slow 0.00001 FTDNA
578 slow 0.00008 FTDNA
426 slow 0.00009 FTDNA, SMGF
454 slow 0.00016 FTDNA, SMGF
455 slow 0.00016 FTDNA, SMGF
425 slow 0.00018 FTDNA
436 slow 0.00018 FTDNA
641 slow 0.00018 FTDNA
490 slow 0.00019 FTDNA
450 slow 0.0002 FTDNA
388 slow 0.00022 FTDNA, SMGF
594 slow 0.00029 FTDNA
395s1 slow 0.00031 FTDNA
395s1 slow 0.00031 FTDNA
640 slow 0.00034 FTDNA
531 slow 0.00037 FTDNA
492 slow 0.00042 FTDNA
617 slow 0.00042 FTDNA
392 slow 0.00052 FTDNA, SMGF
462 slow 0.00053 SMGF
568 slow 0.00053 FTDNA
590 slow 0.00054 FTDNA
438 slow 0.00055 FTDNA, SMGF
537 slow 0.00057 FTDNA
393 slow 0.00076 FTDNA, SMGF
565 slow 0.00087 FTDNA
B07 slow 0.00093 SMGF
445 slow 0.000952 SMGF
487 slow 0.00097 FTDNA
437 slow 0.00099 FTDNA, SMGF
YCAIIa medium 0.00123 FTDNA, SMGF
YCAIIb medium 0.00123 FTDNA, SMGF
511 medium 0.00128 FTDNA
441 medium 0.00132 SMGF
459a medium 0.00132 FTDNA, SMGF
459b medium 0.00132 FTDNA, SMGF
448 medium 0.00135 FTDNA, SMGF
19 medium 0.00151 FTDNA, SMGF
406s1 medium 0.00154 FTDNA
463 medium 0.00162 SMGF
452 medium 0.001743 SMGF
389i medium 0.00186 FTDNA, SMGF
413a medium 0.00202 FTDNA
413b medium 0.00202 FTDNA
H4 medium 0.00208 FTDNA, SMGF
572 medium 0.00212 FTDNA
385a medium 0.00226 FTDNA, SMGF
385b medium 0.00226 FTDNA, SMGF
461 medium 0.00233 SMGF
C4 medium 0.00236 SMGF
389ii medium 0.00242 FTDNA, SMGF
520 medium 0.00245 FTDNA
447 medium 0.00264 FTDNA, SMGF
391 medium 0.00265 FTDNA, SMGF
390 medium 0.00311 FTDNA, SMGF
444 medium 0.00321 FTDNA, SMGF
557 medium 0.00321 FTDNA
442 medium 0.00324 FTDNA, SMGF
446 medium 0.00365 FTDNA, SMGF
A10 medium 0.00379 SMGF
460 medium 0.00402 FTDNA, SMGF
607 medium 0.00411 FTDNA
439 medium 0.00477 FTDNA, SMGF
481 fast 0.00544 FTDNA
464a fast 0.00566 FTDNA, SMGF
464b fast 0.00566 FTDNA, SMGF
464c fast 0.00566 FTDNA, SMGF
464d fast 0.00566 FTDNA, SMGF
456 fast 0.00735 FTDNA, SMGF
570 fast 0.0079 FTDNA
458 fast 0.00814 FTDNA, SMGF
534 fast 0.00832 FTDNA
449 fast 0.00838 FTDNA, SMGF
576 fast 0.01022 FTDNA
CDYa fast 0.03531 FTDNA
CDYb fast 0.03531 FTDNA
Following are some other references on TMRCA etc...
http://nitro.biosci.arizona.edu/ftdna/TMRCA.htm
http://members.aol.com/dnafiler/MutationCalculator.exe
(Anne Turner's Time to MRCA calculator)
http://www.bearport.org/Downloads/MRCAChart-b.4.zip
(alternative Time to MRCA calculator)
http://blairgenealogy.com/dna/markers.html
(Marker analysis)***
http://nitro.biosci.arizona.edu/ftDNA/Distance.html
(Genetic distance calculations)
http://www.cottrellweb.com/dna/mrca-12.htm
(probabilies re TMRCA for 12 markers)
http://www.cottrellweb.com/dna/mrca-25.htm
(probabilies re TMRCA for 25 markers)
http://www.cottrellweb.com/dna/mrca-37.htm
(probabilies re TMRCA for 37 markers)
http://www.cottrellweb.com/dna/mrca-43.htm
(probabilies re TMRCA for 43 markers)
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